Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FTY720 (S)-Phosphate is an S1P receptor 1 (S1PR1) agonist. It is used in the research of acute inflammatory diseases such as acute lung injury.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,710.00 | |
50 mg | 8-10 weeks | $ 2,230.00 | |
100 mg | 8-10 weeks | $ 3,100.00 |
Description | FTY720 (S)-Phosphate is an S1P receptor 1 (S1PR1) agonist. It is used in the research of acute inflammatory diseases such as acute lung injury. |
In vitro | FTY720 (S)-Phosphate (0.01-50 μM) also reduces β-arrestin recruitment to S1PR1. FTY720 (S)-Phosphate (Tys, 1 μM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1. But it shows no effect on inducing ubiquitination of S1PR1 [1]. |
In vivo | FTY720 (S)-Phosphate, administered intraperitoneally at a dose of 0.5 mg/kg, maintains S1PR1 expression in mouse lungs and offers protection against acute lung injury (ALI) induced by bleomycin. Additionally, it reduces leukocyte infiltration in the lung tissues of mice injured with bleomycin [1]. |
Synonyms | (S)-FTY720 phosphate, (S)-FTY720P |
Molecular Weight | 387.45 |
Formula | C19H34NO5P |
CAS No. | 402616-26-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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FTY720 (S)-Phosphate 402616-26-6 Others FTY720 (S) Phosphate FTY720 Phosphate FTY720 (S)Phosphate FTY720P (S)-FTY720 phosphate (S)-FTY720P FTY-720 (S)-Phosphate FTY-720 Phosphate FTY 720 Phosphate inhibitor inhibit