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Search Results for " flt-3-in-3 "

11

Compounds

Cat No. Product Name Synonyms Targets
T11298 FLT3-IN-3 FLT
FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.
T1938 FLT3-IN-2 FLT
FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).
T11299 FLT3-IN-4 FLT3 inhibitor 9u FLT
FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenous leukemia.
T11300 FLT3-IN-6 Others
FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM.
T72407 C-Met/MEK1/Flt-3-IN-1
Antiproliferative Against-3 (comp 33) demonstrates significant activity against Hela (IC 50 = 0.21 µM), A549 (IC 50 = 0.39 µM), and MCF-7 (IC 50 = 0.33 µM) cell lines. Additionally, it induces apoptosis in a dose-depende...
T24067 Flt3 Inhibitor IV Flt3 Inhibitor-IV,Flt3-IN-IV
Flt3 Inhibitor IV is a potent ATP-competitive Flt3 inhibitor.
T2272 BPR1J-097 BPR1J097 FLT
BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).
T4261 BPR1J-097 hydrochloride (1327167-19-0(free base)) FLT
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
T2624 OSI-930 OSI 930 Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T39818 Desmorpholinyl Quizartinib-PEG2-COOH Desmorpholinyl Quizartinib-PEG2-COOH
Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal ta...
T68389 LY2457546
LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involved in angiogenic and tumorigenic signalling. LY2457546 demonstrates potent activity against targets that include VEGFR2 ...
TargetMol