fgfr2-in-3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60185	FGFR2-IN-3		FGFR
	FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1].		FGFR
T63850	FGFR2-IN-3 hydrochloride
	FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.
T5044	Futibatinib	TAS120,FGFR-IN-1	FGFR
	Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.		FGFR
T1948	AZD4547		VEGFR , FGFR
	AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).		VEGFR , FGFR
T2638	Gandotinib	LY2784544	VEGFR , FGFR , FLT , JAK
	LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.		VEGFR , FGFR , FLT , JAK
T73146	FGFR3-IN-5
	FGFR3-IN-5 is a potent, selective FGFR3 inhibitor, exhibiting IC50 values of 3 nM (FGFR3), 44 nM (FGFR2), and 289 nM (FGFR1), respectively. This compound is utilized in cancer research.
T3512	S49076 HCl	S-49076 Hydrochloride	FGFR , c-Met/HGFR , TAM Receptor
	S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 HCl potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream signaling in vitro and in ...		FGFR , c-Met/HGFR , TAM Receptor