Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 53.00 | |
5 mg | In stock | $ 124.00 | |
10 mg | In stock | $ 182.00 | |
25 mg | In stock | $ 349.00 | |
50 mg | In stock | $ 538.00 | |
100 mg | In stock | $ 697.00 | |
200 mg | In stock | $ 995.00 | |
500 mg | In stock | $ 1,470.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 136.00 |
Description | Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment. |
Targets&IC50 | FGFR2 (E566G):2.4 nM (IC50), FGFR2 (N550H):3.6 nM (IC50), FGFR4:8.3 nM (IC50), FGFR3:1.6 nM (IC50), FGFR2 (WT):0.3 nM (IC50), FGFR2 (V5651):1-3 nM (IC50), FGFR1:3.9 nM (IC50), FGFR2:1.3 nM (IC50) |
In vitro | TAS-120 (3, 30, 100 mg/kg/day, p.o.) exerts an anti-tumor effect in mice. TAS-120 shows anti-tumor effect by administering at moderate intervals, such as intermittent administration of every other day dosing and 2 times/week, and reducing the sustained elevation and weight suppression blood phosphorus level, and take a antitumor effective as daily administration. |
Synonyms | TAS120, FGFR-IN-1 |
Molecular Weight | 418.45 |
Formula | C22H22N6O3 |
CAS No. | 1448169-71-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (119.49 mM)
You can also refer to dose conversion for different animals. More
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Futibatinib 1448169-71-8 Angiogenesis Tyrosine Kinase/Adaptors FGFR TAS-120 Inhibitor TAS120 TAS 120 FGFR-IN-1 Fibroblast growth factor receptor inhibit inhibitor