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Search Results for " ffar "

20

Compounds

Cat No. Product Name Synonyms Targets
T7796 TUG-1375 GPR
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2
T15810 LY2922470 GPR
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava...
T11458 GPR40/FFAR1 modulator 1 GPR
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
T3433 TUG-891 TUG 891,TUG891 GPR
TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids.
T2351 Fasiglifam TAK875 GPR
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist.
T7127 DC260126 Apoptosis , GPR
DC260126 is a small-molecule antagonist of FFA1 (GPR40)
T8642 4-CMTB GPR
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38).
TQ0020 AMG 837 calcium hydrate GPR
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).
T15413 GPR120 Agonist 3 GPR120-IN-1 GPR
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62).
T22027 AH-7614 AH 7614 GPR
AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.
T4312 GPR120 Agonist 2 GPR120 receptor agonist GPR
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist.
T22967 MEDICA16 MEDICA 16 GPR , Others , ATP Citrate Lyase
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insu...
T3171 GSK137647A GSK 137647 GPR
GSK137647A (GSK 137647) is a selective FFA4 agonist.
T1781 GW9508 GW 9508 GPR , Potassium Channel
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T3919 Ginsenoside Rb2 Ginsenoside C GPR , Others , Influenza Virus , Endogenous Metabolite
Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.
T12883 Fezagepras PBI-4050,Setogepram GPR
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.
T1286 Vincamine Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval GPR , Others
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
T21893 Luffariellolide
Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 ( HSF-PLA2 ) (IC 50 =5 μM). PMA-induced ear edema was effectively inhibited by luffariellolide (ED 50 =50 μg/ear) [1].
T32941 Luffariolide G
Luffariolide G is a manoalide derivative isolated from the Okinawan marine sponge Luffariella.
T32940 Luffariolide F
Luffariolide F is a manoalide derivative isolated from the Okinawan marine sponge Luffariella.
TargetMol