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Search Results for " fcrn "

Targets

6

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T39057 Rozanolixizumab UCB7665 Others
Rozanolixizumab (RYSTIGGO) is a high-affinity humanized immunoglobulin G4 monoclonal antibody targeting Fc receptors (FcRn) in human newborns for the study of pathogenic IgG in autoimmune and alloimmune diseases.
T78249 Nipocalimab M281
Nipocalimab (M281), a fully human, recombinant, aglycosylated IgG1 monoclonal antibody, exhibits high-affinity binding to the Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6, characterized by its pic...
T78245 Batoclimab IMVT-1401,HBM9161
Batoclimab, a human anti-FcRn monoclonal antibody, is utilized in the study of IgG-mediated autoimmune diseases [1].
T78325 Orilanolimab SYNT001
Orilanolimab (SYNT001) is a humanized, de-immunized monoclonal antibody that inhibits the FcRn-IgG interaction, thereby disrupting IgG homeostasis and impeding FcRn-mediated adaptive immune responses, as well as related ...
T9901A-010 Tifalibep ABY-039
Tifalibep (ABY-039) is a bivalent anti-FcRn antibody mimetic that can be used to treat antibody (IgG)-mediated autoimmunity.
T77190 Crovalimab
Crovalimab (SKY59; RO7112689) is a novel humanized antibody designed to target C5 in a pH-dependent manner, demonstrating binding affinities (KD) of 15.2 nM and 16.8 μM at pH levels of 7.4 and 5.8, respectively. Addition...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02811 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is Q61559&P01887.
TMPY-05539 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899&P61769.
TMPY-02082 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.5 kDa and the accession number is P55899-1&P61769.
TMPY-05649 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 46 kDa and the accession number is Q61559.
TMPY-05147 FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
FCGRT & B2M Heterodimer Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.2 kDa and the accession number is Q61559&P01887.
TMPY-05036 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098.1&NP_004039.1.
TMPY-05448 FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
FCGRT & B2M Heterodimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.3 kDa and the accession number is NP_004098....
TMPH-01517 FCGRT Protein, Human, Recombinant (GST) Human E. coli
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound...
TMPH-01516 FCGRT Protein, Human, Recombinant (His) Human HEK293 Cells
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound...
TMPK-01115 Fc gamma RIII/CD16 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, ...
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