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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8480 | Tenovin-6 Hydrochloride | Dehydrogenase , Sirtuin , HDAC , p53 , Autophagy | |
Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 μM, 10 μM, and 67 μM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator . | |||
T1818 | Tenovin-6 | Tenovin 6 | Dehydrogenase , Sirtuin , Autophagy |
Tenovin-6 is a p53 transcriptional activity agonist. | |||
T1919 | Tenovin-1 | Tenovin 1 | Mdm2 , Dehydrogenase , Sirtuin , p53 , Autophagy |
Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination. | |||
T1873 | Tenovin-3 | Tenovin3 | Sirtuin |
Tenovin-3 acts as a p53 activator. | |||
T4642 | Tenovin-2 | Others | |
Tenovin-2 has a wide range of applications in life science related research. | |||
T26259 | Tenovin-D3 | TenovinD3 | |
Tenovin-D3 is a sirtuin SirT2 inhibitor. It acts by increasing p21 (CDKN1A) expression in a p53-independent manner. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00100 | Artemin Protein, Human, Recombinant | Human | E. coli |
Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a variable length pre-, or signal sequence, plus a 68 amino acid (... | |||
TMPK-00109 | Artemin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored... |