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Search Results for " eln "

Targets

17

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T2086 ELN-441958 ELN 441958 Bradykinin Receptor
ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors.
T11178L ELN318463 racemate ELN318463 (racemate),ELN 318463 racemate Gamma-secretase
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
T4659 ELN484228 Others
ELN484228 is a α-synuclein blocker. α-synuclein is a key protein in Parkinson’s disease.
T11178 ELN318463 ELN 318463 Others
ELN 318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN 318463 is 51-fold more selective for PS1.ELN 318463 is an amyl...
T0121 Azelnidipine CS 905,UR-12592 Calcium Channel
Azelnidipine (UR-12592) is a dihydropyridine used as calcium channel blocker.
T61786 Selnoflast RG 6418,RO-7486967 NOD
Selnoflast (example 6) is a NLRP3 inhibitor[1].
T6090 Belnacasan VX-765 Caspase
Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.
T17222 Velneperit S2367 Neuropeptide Y Receptor
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
T78613 Selnoflast calcium RO-7486967 calcium NOD-like Receptor (NLR)
Selnoflast calcium (example 6), an NLRP3 inhibitor[1], is a chemical compound designed to suppress the activity of the NLRP3 inflammasome.
T78614 Selnoflast potassium RO-7486967 potassium NOD-like Receptor (NLR)
Selnoflast (potassium) (example 6), is an NLRP3 inhibitor.
T70951 ELND006
ELND006 is a novel gamma secretase inhibitor previously under investigation for the oral treatment of Alzheimer's disease. ELND006 shows poor solubility and has moderate to high permeability. The in vivo performance of t...
T68806 Azelnidipine, (S)-
Azelnidipine, (S)-, is an L-type calcium channel blocker (CCB). Studies have shown that in patients with hypertension (HT) and heart failure preserved ejection fraction (HFpEF), azelnidipine improved the severity of HF a...
T10439 Azelnidipine D7 CS-905 D7 Others
Azelnidipine D7 is a deuterium-labeled Azelnidipine. Azelnidipine is an L-type calcium channel blocker.
T68807 Azelnidipine, (R)-
Azelnidipine, (R)-, is an L-type calcium channel blocker (CCB). Studies have shown that in patients with hypertension (HT) and heart failure preserved ejection fraction (HFpEF), azelnidipine improved the severity of HF a...
T70635 ELND007
ELND007 is a Gamma secretase inhibitor.
T35045 Velnacrine 1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate,1-hydroxytacrine,9-ATHCO,9-amino-1,2,3,4-tetrahydroacridin-1-ol Others
Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.
TNU1448 NovelN4-Benzoyl-7’-O-(4,4’-dimethoxytrityl oxy)morpholinocytosine
novelN4-Benzoyl-7'-O-(4,4'-dimethoxytrityl oxy)morpholinocytosine is a Nucleoside Derivative - Morpholino nucleoside.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-02636 Elastin Protein, Mouse, Recombinant (His) Mouse E. coli
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulat...
TMPK-00946 EFEMP1 Protein, Human, Recombinant (His) Human HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correla...
TMPK-01082 EFEMP1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correla...
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