Search Result

Search Results for " er-alpha "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Targets
T22767	ER 50891	Retinoid Receptor
	ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.	Retinoid Receptor
T70013	Pipendoxifene
	Pipendoxifene, also known as ERA-923, is a new antiestrogen with potential anticancer activity. ERA-923 potently inhibits estrogen binding to ER-alpha (IC50 = 14 nM). In ER-alpha-positive human MCF-7 breast carcinoma cel...
T18607	PROTAC ER Degrader-3	Others
	PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody,...	Others
T18606	PROTAC ER Degrader-2	Others
	PROTAC ER Degrader-2 serves as a synthesis intermediate for the production of PAC, a compound that incorporates the ADCs linker and PROTACs, which are subsequently conjugated to an antibody. PAC, exhibits a greater capab...	Others
T70399	TTC-352
	TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring...
T68292	GTX-758
	GTX-758, also known as Capesaris, is a n orally available, nonsteroidal selective estrogen receptor (ER) alpha agonist with potential antineoplastic activity. Upon administration of GTx-758, this agent suppresses the sec...

Compounds

ER 50891

T22767

Synonym:

Target: Retinoid Receptor

Cat No.	Product Name	Synonyms	Targets
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...

Natural Products

(-)-(S)-Equol

T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00762	ER alpha Protein, Human, Recombinant (His)	Human	E. coli
	Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and a...
TMPJ-01384	MAN1B1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Endoplasmic Reticulum Mannosyl-Oligosaccharide 1,2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is invo...
TMPY-03870	EDEM2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EDEM2, also known as C2orf31, belongs to a family of proteins involved in ER-associated degradation (ERAD) of glycoproteins. In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and ...
TMPH-01305	ER beta Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ...
TMPH-01304	ER beta Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ...
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7)	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPJ-01212	ULBP-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2...
TMPY-04422	Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily. It may affect the development of brain, and associate with vesicular trafficking and neurotran...