e-64 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6037	E-64	Proteinase inhibitor E 64,E 64,E64	Cysteine Protease , Antibacterial , Autophagy
	E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.		Cysteine Protease , Antibacterial , Autophagy
T6573	E 64c	NSC 694279,EP 475,Loxistatin Acid	SARS-CoV , Cysteine Protease
	E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.		SARS-CoV , Cysteine Protease
T11888	LtaS-IN-1		Others , Antibacterial
	LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC value...		Others , Antibacterial
T82834	Bombinin-BO1
	Bombinin-BO1, an antimicrobial peptide from the skin secretions of the Bombina orientalis toad, exhibits activity against E. coli, S. aureus, and Candida albicans with minimum inhibitory concentration (MIC) values of 64,...
T38259	Phenelfamycin E
	Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) inc...
T38917	Antibacterial agent 50
	Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351...
T78673	Antibacterial agent 135
	Antibacterial Agent 135 (example 7) effectively inhibits various bacteria, including P. aeruginosa, A. baumannii, E. coli, and K. pneumoniae, with a minimum inhibitory concentration (MIC) greater than 64 μg/mL [1].
T39790	LpxC-IN-5
	LpxC-IN-5 is a potent, non-hydroxamate inhibitor of LpxC, which is an enzyme known as UDP-3-O-acyl-N-acetylglucosamine deacetylase. It exhibits an IC50 value of 20 nM. Furthermore, LpxC-IN-5 displays antibacterial activi...
T36746	Leoidin
	Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.1,2,3 It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S...
T83705	BING TFA	Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
	BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gra...
T37874	Feglymycin
	Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replica...
T38382	8Br-HA
	8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively). 1.Kawaguchi, M., Se...
T36110	L-Pyrohomoglutamic Acid
	L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A....
T36649	AN3661
	AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains...
T35683	2-deoxy-D-Glucose-13C6	2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h...
T35881	Resolvin E2
	Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-...