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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10093L | E1R | Others | |
E1R is a positive sigma-1 receptor (Sig1R PAM) allosteric modulator. It has a cognition-enhancing activity. | |||
T12665 | (Rac)-E1R | Others | |
(Rac)-E1R is the racemate of E1R. (Rac)-E1R is a sigma-1 receptor positive allosteric (Sig1R PAM) modulator of for the treatment of cognition/memory disorders. | |||
T10097 | (2S,3S)-E1R | Others | |
(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders. | |||
T10094 | (2R,3S)-E1R | Others | |
(2R,3S)-E1R (Compound 2c) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders. | |||
T10093 | (2R,3R)-E1R | Others | |
(2R,3R)-E1R is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders. | |||
T3570 | SU4312 | SU 4312,NSC 86429 | VEGFR , PDGFR |
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox... | |||
T6S1487 | Ginsenoside Rg5 | NF-κB , COX , IGF-1R | |
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ... | |||
T70276 | Roridin E | ||
Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFRβ, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 μM, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM). It al... |