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Cat No. | Product Name | Synonyms | Targets |
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T14983 | Clomethiazole | Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | P450 , GABA Receptor |
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C... | |||
T31433 | Dichlobenil | Decabane,Casoron 133,Norosac,Casoron,Cyclomec | |
Dichlobenil is a herbicide and is slightly toxic for humans. It is metabolized in the liver by the enzyme CYP2A6. | |||
T78135 | Nicotelline | Nicotellin | |
Nicotelline, also known as Nicotellin, is an alkaloid associated with nicotine and acts as a modest inhibitor of the enzyme human cDNA-expressed cytochrome P-450 2A6 (CYP2A6), which is responsible for coumarin 7-hydroxyl... | |||
T7788 | 2-Phenyl-2-(1-piperidinyl)propane | Others | |
2-Phenyl-2-(1-piperidinyl)propane (PPP), an analog of phencyclidine |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11218 | ε-Viniferin | epsilon-Viniferin | P450 |
ε-Viniferin (epsilon-Viniferin) a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities. | |||
T2770 | Gentiopicroside | Gentiopicrin | P450 , HCV Protease |
Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya... | |||
T3818 | Fraxinol | Others , P450 | |
Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an... | |||
T3811 | Ginsenoside C-K | Ginsenoside compound K,Ginsenoside K | P450 , cell cycle arrest , COX , NO Synthase |
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2. | |||
TN3294 | 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate | NADPH-oxidase , P450 , MAO | |
8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. | |||
TN3300 | 8alpha-Tigloyloxyhirsutinolide 13-O-acetate | NADPH-oxidase , P450 , MAO | |
8alpha-Tigloyloxyhirsutinolide 13-O-acetate shows inhibitory activity toward CYP2A6 and MAO-A and MAO-B enzymes. 8alpha-Tigloyloxyhirsutinolide 13-O-acetate has anti-cancer activity, it is active against both cancer cell... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01184 | CYP2A6 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
CYP2A6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. |