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Search Results for " cddo "

7

Compounds

Cat No. Product Name Synonyms Targets
T10733 CDDO-EA TP319,CDDO ethyl amide,RTA 405 Nrf2
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
T13602 CDDO-2P-Im CDDO-2-P-Im Others
CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.
TQ0120 CDDO-Im RTA-403,CDDO-Imidazolide,TP-235 Others , Ferroptosis , Nrf2 , PPAR
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).
T13604 CDDO-dhTFEA Others , NF-κB , Nrf2
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expressi...
T13603 CDDO-3P-Im Necroptosis
CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion.
T2915 Bardoxolone RTA 401,CDDO Others , Nrf2
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...
T6165 Bardoxolone Methyl RTA 402,CDDO Methyl ester,TP-155,NSC 713200 Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.
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