7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10733 | CDDO-EA | TP319,CDDO ethyl amide,RTA 405 | Nrf2 |
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element. | |||
T13602 | CDDO-2P-Im | CDDO-2-P-Im | Others |
CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model. | |||
TQ0120 | CDDO-Im | RTA-403,CDDO-Imidazolide,TP-235 | Others , Ferroptosis , Nrf2 , PPAR |
CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ). | |||
T13604 | CDDO-dhTFEA | Others , NF-κB , Nrf2 | |
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expressi... | |||
T13603 | CDDO-3P-Im | Necroptosis | |
CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion. | |||
T2915 | Bardoxolone | RTA 401,CDDO | Others , Nrf2 |
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp... | |||
T6165 | Bardoxolone Methyl | RTA 402,CDDO Methyl ester,TP-155,NSC 713200 | Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy |
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities. |