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Search Results for " ccr1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10708 CCR1 antagonist 6 CCR
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
T15253 CCX354 CCR1 antagonist 1,CCX-354,CCX 354 CCR
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.
T30258 AZD-4818 CCR1 antagonist CCR
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.
T77349 CCR1/5/8 activator 1 Phospholipase
CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity.
T10710 CCR1 antagonist 9 CCR
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay).
T10709 CCR1 antagonist 7 CCR
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].
T14899 CCR1 antagonist 8 CCR
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay).
T64242 CCR1 antagonist 11 hydrochloride
CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist that acts on hCCR1 (IC50: 0/.03 μM), mCCR1 (IC50: 0.58 μM), rCCR1 (IC50: 0.32 μM). 11 hydrochloride can be used to study rheumatoid arthritis an...
T28072 MLN-3897 AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897 CCR
MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation.
T11699 J-113863 CCR
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor...
T2375 BX471 BX 471,BX-471,ZK-811752 CCR
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.
T26861 BMS-817399 BMS817399 CCR
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis.
T28072L MLN-3897 TFA MLN-3897 TFA(1010731-97-1 Free base) CCR
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.
T3188 RE-640 CCR , Parasite
NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
TQ0283 RS102895 CCR
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
T5384 RS 504393 CCR
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).
T14845 BX471 hydrochloride ZK-811752 hydrochloride Others
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
T23492 UCB 35625 Others
chemokine CCR1 and CCR3 receptor antagonist
T31061 CP-481715 CP 481,715,CP-481,715,CP481715,CP481,715
CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.
T26849 BMS-457
BMS-457 is a potent, CCR1-selective antagonist.
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