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CCR1 antagonist 6

Name: CCR1 antagonist 6
Brand: TargetMol
SKU: T10708
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10708Cas No. 2436773-01-0

CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).

CCR1 antagonist 6

🥰Excellent

Purity: 99.92%

Catalog No. T10708Cas No. 2436773-01-0

CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$160	In Stock	In Stock
5 mg	$377	In Stock	In Stock
10 mg	$498	In Stock	In Stock
25 mg	$721	In Stock	In Stock
50 mg	$969	In Stock	In Stock
100 mg	$1,280	-	In Stock
200 mg	$1,760	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.92%

Resource Download

COA HNMR ORP LCMS

Product Introduction

Bioactivity

Description	CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
Targets&IC50	CCR1:3 nM

Chemical Properties

Molecular Weight	446.95
Formula	C₂₁H₂₃ClN₄O₃S
Cas No.	2436773-01-0
Smiles	CC=1N(N=CC1C(N[C@@H](CCC)C=2C=C(S(C)(=O)=O)C=NC2)=O)C3=CC=C(Cl)C=C3
Relative Density.	1.33 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (111.87 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2374 mL	11.1869 mL	22.3739 mL	111.8693 mL
5 mM	0.4475 mL	2.2374 mL	4.4748 mL	22.3739 mL
10 mM	0.2237 mL	1.1187 mL	2.2374 mL	11.1869 mL
20 mM	0.1119 mL	0.5593 mL	1.1187 mL	5.5935 mL
50 mM	0.0447 mL	0.2237 mL	0.4475 mL	2.2374 mL
100 mM	0.0224 mL	0.1119 mL	0.2237 mL	1.1187 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc