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Search Results for " brd4 "

20

Compounds

Cat No. Product Name Synonyms Targets
T14776 BRD4 Inhibitor-10 Epigenetic Reader Domain
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
T78555 BRD4 Inhibitor-27 Epigenetic Reader Domain
BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research.
T77339 BRD4-IN-4 Epigenetic Reader Domain
BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL...
T12551 PROTAC BRD4 ligand-1 Epigenetic Reader Domain , Ligands for Target Protein for PROTAC
PROTAC BRD4 ligand-1 is a ligand for BRD4 for Protac GNE-987 and an inhibitor of BET.
T9629 BRD4 Inhibitor-24 Epigenetic Reader Domain
BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.
T40305 BRD4-IN-2 BRD4-IN-2
BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC 50 value of 9.9 nM.
T61318 BRD4 Inhibitor-20 Epigenetic Reader Domain
BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity. BRD4 Inhibitor-20 has antiproliferative activity in cancer cell lines and is used in studies of various cancers, such as colon canc...
T40073 PROTAC BRD4 Degrader-10 PROTAC BRD4 Degrader-10
PROTAC BRD4 Degrader-10, also known as compound 8b, is a dual ligand-based PROTAC that combines ligands for von Hippel-Lindau and BRD4. To degrade the BRD4 protein in PC3 prostate cancer cells, PROTAC BRD4 Degrader-10 ca...
T40075 PROTAC BRD4 Degrader-13 PROTAC BRD4 Degrader-13
PROTAC BRD4 Degrader-13 (compound 9d) is a bioactive compound that functions as a proteolysis targeting chimera (PROTAC), linking ligands for von Hippel-Lindau and BRD4 proteins. In the context of PC3 prostate cancer cel...
T40074 PROTAC BRD4 Degrader-15 PROTAC BRD4 Degrader-15
PROTAC BRD4 Degrader-15 is a chemical compound consisting of a PROteolysis TArgeting Chimera (PROTAC) linked to ligands specific to von Hippel-Lindau and BRD4. It exhibits an IC50 of 7.2 nM for BRD4 BD1 and 8.1 nM for BR...
T36242 PROTAC BRD4 Degrader-5 PROTAC BRD4 Degrader-5
PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines[1].
T36628 PROTAC BRD4 Degrader-8 PROTAC BRD4 Degrader-8
PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells...
T39628 PROTAC BRD4 ligand-2 PROTAC BRD4 ligand-2
PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
T40072 PROTAC BRD4 Degrader-9 PROTAC BRD4 Degrader-9
PROTAC BRD4 Degrader-9 (compound 8a) is a novel chemical compound consisting of ligands for von Hippel-Lindau and BRD4, connected by a PROTAC moiety. This compound can effectively degrade the BRD4 protein in PC3 prostate...
T64117 BRD4-BD1-IN-2 Epigenetic Reader Domain
BRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 µM, which is 20-fold greater than the inhibitory activity against BRD4-BD2.BRD4-BD1-IN-2 can be used in the study of cardiovascular an...
T30580 BRD4-Kinases-IN-3 BRD4 kinases inhibitor 3,BRD4-Kinases inhibitor-3
BRD4-Kinases-IN-3 is a dual BRD4-Kinases inhibitor that can be used as a value-added multi-targeted chemical probe for cancer therapy.
T39629 BRD4 ligand-Linker Conjugate 1 BRD4 ligand-Linker Conjugate 1
BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules uti...
T4365 FL-411 FL 411,FL411,BRD4-IN-1 Epigenetic Reader Domain
FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.
T5439 BRD4 degrader AT1 Epigenetic Reader Domain
BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.
T13833 PROTAC BRD4 Degrader-1 Epigenetic Reader Domain
PROTAC BRD4 Degrader-1 is an efficacious degrader of BRD4(BRD4 BD1,IC50 of 41.8 nM).
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TargetMol