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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14776 | BRD4 Inhibitor-10 | Epigenetic Reader Domain | |
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM). | |||
T78555 | BRD4 Inhibitor-27 | Epigenetic Reader Domain | |
BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 μM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research. | |||
T77339 | BRD4-IN-4 | Epigenetic Reader Domain | |
BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL... | |||
T12551 | PROTAC BRD4 ligand-1 | Epigenetic Reader Domain , Ligands for Target Protein for PROTAC | |
PROTAC BRD4 ligand-1 is a ligand for BRD4 for Protac GNE-987 and an inhibitor of BET. | |||
T9629 | BRD4 Inhibitor-24 | Epigenetic Reader Domain | |
BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity. | |||
T40305 | BRD4-IN-2 | BRD4-IN-2 | |
BRD4-IN-2 is a bromodomain BRD4 inhibitor with an IC 50 value of 9.9 nM. | |||
T61318 | BRD4 Inhibitor-20 | Epigenetic Reader Domain | |
BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity. BRD4 Inhibitor-20 has antiproliferative activity in cancer cell lines and is used in studies of various cancers, such as colon canc... | |||
T40073 | PROTAC BRD4 Degrader-10 | PROTAC BRD4 Degrader-10 | |
PROTAC BRD4 Degrader-10, also known as compound 8b, is a dual ligand-based PROTAC that combines ligands for von Hippel-Lindau and BRD4. To degrade the BRD4 protein in PC3 prostate cancer cells, PROTAC BRD4 Degrader-10 ca... | |||
T40075 | PROTAC BRD4 Degrader-13 | PROTAC BRD4 Degrader-13 | |
PROTAC BRD4 Degrader-13 (compound 9d) is a bioactive compound that functions as a proteolysis targeting chimera (PROTAC), linking ligands for von Hippel-Lindau and BRD4 proteins. In the context of PC3 prostate cancer cel... | |||
T40074 | PROTAC BRD4 Degrader-15 | PROTAC BRD4 Degrader-15 | |
PROTAC BRD4 Degrader-15 is a chemical compound consisting of a PROteolysis TArgeting Chimera (PROTAC) linked to ligands specific to von Hippel-Lindau and BRD4. It exhibits an IC50 of 7.2 nM for BRD4 BD1 and 8.1 nM for BR... | |||
T36242 | PROTAC BRD4 Degrader-5 | PROTAC BRD4 Degrader-5 | |
PROTAC BRD4 Degrader-5 is a PROTAC-based BRD4 degrader. PROTAC BRD4 Degrader-5 can potent degrade BRD4 in HER2 positive and negative breast cancer cell lines[1]. | |||
T36628 | PROTAC BRD4 Degrader-8 | PROTAC BRD4 Degrader-8 | |
PROTAC BRD4 Degrader-8 is a potent BRD4 inhibitor, with IC50s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells... | |||
T39628 | PROTAC BRD4 ligand-2 | PROTAC BRD4 ligand-2 | |
PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718. | |||
T40072 | PROTAC BRD4 Degrader-9 | PROTAC BRD4 Degrader-9 | |
PROTAC BRD4 Degrader-9 (compound 8a) is a novel chemical compound consisting of ligands for von Hippel-Lindau and BRD4, connected by a PROTAC moiety. This compound can effectively degrade the BRD4 protein in PC3 prostate... | |||
T64117 | BRD4-BD1-IN-2 | Epigenetic Reader Domain | |
BRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 µM, which is 20-fold greater than the inhibitory activity against BRD4-BD2.BRD4-BD1-IN-2 can be used in the study of cardiovascular an... | |||
T30580 | BRD4-Kinases-IN-3 | BRD4 kinases inhibitor 3,BRD4-Kinases inhibitor-3 | |
BRD4-Kinases-IN-3 is a dual BRD4-Kinases inhibitor that can be used as a value-added multi-targeted chemical probe for cancer therapy. | |||
T39629 | BRD4 ligand-Linker Conjugate 1 | BRD4 ligand-Linker Conjugate 1 | |
BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules uti... | |||
T4365 | FL-411 | FL 411,FL411,BRD4-IN-1 | Epigenetic Reader Domain |
FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4. | |||
T5439 | BRD4 degrader AT1 | Epigenetic Reader Domain | |
BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells. | |||
T13833 | PROTAC BRD4 Degrader-1 | Epigenetic Reader Domain | |
PROTAC BRD4 Degrader-1 is an efficacious degrader of BRD4(BRD4 BD1,IC50 of 41.8 nM). |