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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5858 | Sertindole | Lu 23-174 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy |
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively) | |||
T5826 | Eupalinolide A | HSP | |
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. | |||
T77635 | LSD1-IN-27 | Histone Demethylase , PD-1/PD-L1 | |
LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 p... | |||
T6S2238 | Eupalinolide B | Others | |
Eupalinolide A has the effects of relieving phlegm and relieving cough, clearing away heat and detoxification, diuretic swelling and reducing blood pressure. | |||
TN2590 | 11alpha,12alpha-Oxidotaraxerol palmitate | Others | |
11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780. | |||
TN2184 | Schisanlactone E | Others | |
Schisanlactone E may show moderate cytotoxic activity against the human tumor cell lines Bel-7402, BGC-823, MCF-7 and HL-60. | |||
TN4843 | Pterisolic acid A | Others | |
Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines. | |||
TN3740 | Cyclocommunol | PAFR | |
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced pla... | |||
T83320 | 4'-Demethylpodophyllotoxone | ||
4'-Demethylpodophyllotoxone, an intermediate in the biotransformation pathway of Alternaria alternata S-f6, undergoes further modification with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP). This modification yields a novel ... | |||
TN3429 | Aphagranin A | Others | |
Aphagranin A exhibits strong antiproliferative activity against the growth of six lines of human cancer cells (MCF-7, A549, HepG2, Bel-7402, SGC-7901, and BGC-823. | |||
T83117 | Angeloylbinankadsurin A | ||
Angeloylbinankadsurin A (compound 7), an anti-rheumatoid arthritis (RA) agent, can be extracted from the EtOAc and CH2Cl2 extracts of Black Tiger Beard. It displays inhibitory effects on RA-FLS cells with an IC50 of 11.7... | |||
T78781 | TrxR1-IN-1 | ||
Compound 5j, also known as TrxR1-IN-1, is a TrxR1 inhibitor with an IC50 of 8.8 μM. It exhibits anticancer activity, demonstrating IC50 values of 1.5 μM in MCF-7, 1.7 μM in HeLa, 2.4 μM in BGC-823, 2.8 μM in SW-480, and ... | |||
T36057 | Diallyl Tetrasulfide | ICD-1585 | |
Diallyl tetrasulfide is an organosulfur compound that has been found in A. sativum and has diverse biological activities, including antimicrobial, antioxidant, and anticancer properties.[1],[2],[3],[4] It is active again... |