as2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10381	AS2717638		Others
	AS2717638 is an orally active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist (IC50: 38 nM for hLPA5). It also significantly improves PGF2α-, PGE2-, and AMPA-induced allodynia.		Others
T4359	VAS2870		NADPH
	VAS2870 is an inhibitor of NADPH oxidase (NOX).		NADPH
T8378	AS2863619		CDK , STAT
	AS2863619 is an orally active inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of 0.61 nM and 4.28 nM, respectively).		CDK , STAT
T10382	AS2863619 free base		CDK
	AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells. It is a potent, orally active CDK8 and CDK19 inhibitor (IC50s: 0.61 nM and 4.28 nM). STAT5 act...		CDK
T81039	TAS2R14 agonist-2
	Compound 28.1, also known as TAS2R14 agonist-2, is a potent and selective inhibitor of TAS2R14, exhibiting an EC50 of 72 nM [1].
T70345	JAS239
	JAS239 is a novel carbocyanine dye that binds and competitively inhibits choline kinase (ChoK) intracellularly. JAS239 attenuated choline phosphorylation and viability in a panel of human breast cancer cell lines. Antibo...
T81040	TAS2R14 agonist-1
	TAS2R14 agonist is a potent partial agonist of TAS2R14, displaying an EC50 value of 116.6 ± 23.6 nM [1].
T14328	AS2521780		PKC
	AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).		PKC
T26664	AS2553627	AS 2553627,AS-2553627
	AS2553627 is a JAK inhibitor. AS2553627 prevents chronic rejection in rat cardiac allografts.
T69912	AS2541019
	AS2541019 is a selective Phosphatidylinositol-3-kinase p110δ (PI3Kδ) inhibitor.
T70373	AS2575959
	AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.

Compounds

AS2717638

T10381

Synonym: AS 2553627,AS-2553627

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00670	ARSA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ARSA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.5 kDa and the accession number is P50428.
TMPH-00056	Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)	Anemonia sulcata	P. pastoris (Yeast)
	Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent...
TMPJ-00705	BCAS2 Protein, Human, Recombinant (His, T7)	Human	E. coli
	Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell li...
TMPH-02005	RRAS2 Protein, Human, Recombinant (GST)	Human	E. coli
	RRAS2 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-02336	TAS2R10 Protein, Human, Recombinant (His & KSI)	Human	E. coli
	Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. TAS2R10 Prot...
TMPH-02715	HAS2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	HAS2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.9 kDa and the accession number is P70312.