apd — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2088	APD668	APD 668	GPR , P450 , Potassium Channel
	APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.		GPR , P450 , Potassium Channel
T14302	Olorinab	APD 371	Cannabinoid Receptor
	Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.		Cannabinoid Receptor
TQ0227	Etrasimod	APD334	S1P Receptor , LPL Receptor
	Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).		S1P Receptor , LPL Receptor
T4635	Ralinepag	APD811	Others , Prostaglandin Receptor
	Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.		Others , Prostaglandin Receptor
T71605	APD-916 dicitrate
	APD-916 dicitrate is a potent and selective inverse agonist of the histamine H3 receptor.
T33793	Olpadronic acid	Me2 APD,Me2-APD,Me2APD
	Olpadronic acid is a biochemical.
T3176	APD597	JNJ-38431055	GPR
	APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.		GPR
T17033	Temanogrel	APD791	5-HT Receptor
	Temanogrel (APD791) is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).		5-HT Receptor
T0811L	Amisulpride hydrochloride	APD-421,Amisulpride HCl,APD 421,APD421,Sultopride
	Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.
T7350	Nelotanserin	APD125	5-HT Receptor
	Nelotanserin (APD125) is a potent 5-HT2A inverse agonist(IC50 : 1.7 nM), a moderately potent 5-HT2C partial inverse agonist t(IC50 :79 nM )and a weak 5-HT2B inverse agonistt(IC50 : 791 nM).		5-HT Receptor
T24801	SKF-77434, (S)-	S-(-)-Apd,J482.833J,S-(-)-SKF-77434
	SKF-77,434 is a drug that acts as a selective dopamine D1 receptor partial agonist. It also has stimulant and anorectic effects.
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
T24095	PAPD5-IN-1	GNE9278,GNE 9278,GNE-9278
	GNE-9278 is an NMDA receptor positive allosteric modulator. It acts via the transmembrane domain.
T81043	Tapderimotide	hTERT (691–705)
	Tapderimotide (hTERT (691–705)) serves as an immunological agent for active immunization [1] [2].
T10095	(2R,4R)-APDC		Others
	(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.		Others