alr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2013	Ponalrestat		Reductase
	Ponalrestat is an aldose reductase inhibitor.		Reductase
T14303	Alrizomadlin	APG-115,AA-115	Mdm2
	Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-d...		Mdm2
T7604	Valrubicin	Valstar,AD-32	Antibiotic , PKC
	Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.		Antibiotic , PKC
T3562	Valrocemide	TV1901,N-Valproylglycinamide	Others
	Valrocemide (TV1901), also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is an anticonvulsant agent under ...		Others
T77523	ALR2-IN-1		Reductase
	ALR2-IN-1 is a potent and selective ALR2 inhibitor with an IC50 value of 1.42 μM.ALR2-IN-1 possesses both antiglycemic and antioxidant activities and can be used to study the complications of diabetes.		Reductase
T33389	Minalrestat	ARI509,WAY-121509,WAY121509,WAYARI-509,ARI-509,WAY-ARI-509	Reductase
	Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.		Reductase
T1458	Epalrestat	ONO2235	Reductase
	Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particul...		Reductase
T1832	Walrycin B		Antibacterial , Antibiotic
	Walrycin B is a new-type antibacterial compound targeting the WalR response regulator.		Antibacterial , Antibiotic
T5195	Alrestatin	AY-22284	Reductase
	Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro.		Reductase
T76252L	WLSEAGPVVTVRALRGTGSW TFA
	WLSEAGPVVTVRALRGTGSW TFA, a cardiomyocyte-specific peptide, exhibits enhanced performance through its expression in exosomes, which notably improves uptake by cardiomyocytes, reduces apoptosis within these cells, and inc...
T70610	ALRN-6924
	ALRN-6924 is a novel dual MDM4 and MDM2 inhibitor.
T62456	ALR1/2-IN-1
	ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) (IC50: 3.26 μM) and aldose reductase (ALR2) (IC50: 3.06 μM) inhibitor with anticancer effects.
T5195L	Alrestatin Sodium	AY 22284A,AY-22284A,Alrestatine sodium,AY22284A
	Alrestatin is a specific inhibitor of the aldose reductase enzyme.
T83135	Alrefimotide	hTERT (660–689)
	Alrefimotide, an immunogenic peptide derived from hTERT, possesses the sequence ALFSVLNYERARRPGLLGASVLGLDDIHRA and has applications in cancer immunotherapy research [1].
TN2271	Thalrugosaminine		Antifection
	Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug/ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotensive activity in rabbits and is active ag...		Antifection
T26601	ALRT 1550	LG-1550,LGD-1550,ALRT-1550,LG1550,ALRT-550,ALRT1550
	ALRT 1550, a retinoic acid agent (RAR) agonist, is used potentially for the treatment of cervical carcinoma.
T73305	ALR2-IN-3
	ALR2-IN-2, a potent aldose reductase (ALR2) inhibitor, demonstrates IC50 values of 22 nM for rat ALR2 and 116 nM for ALR1, respectively. This compound is utilized in diabetic complications research.
T73304	ALR2-IN-2
	ALR2-IN-2, a potent aldose reductase (ALR2) inhibitor, exhibits IC50 values of 27 nM for rat ALR2 and 228 nM for ALR1, respectively. This compound is utilized in the research of diabetic complications.
TN5140	Thalrugosidine		Others
	Thalrugosidine is a natural product from Thalictrum foliolosum DC.		Others
T60186	(S)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide		Discoidin Domain Receptor (DDR)
	MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cyto...		Discoidin Domain Receptor (DDR)