17
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10212 | A2AR-agonist-1 | N-(2-(1H-Indol-3-yl)ethyl)adenosine | Others , Adenosine Receptor |
A2AR-agonist-1 (N-(2-(1H-Indol-3-yl)ethyl)adenosine) is a potent A2AR and ENT1 agonist (Ki: 4.39 and 3.47 for A2AR and ENT1. It targets the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection. | |||
T72626 | A2AR-antagonist-1 | Adenosine Receptor | |
A2AR-antagonist-1 (compound 38), an orally active adenosine A2A receptor antagonist with an IC50 value of 29 nM, demonstrates anti-tumor properties and stability in mouse liver microsomes (t1/2 = 86.1 min). Additionally,... | |||
T12163 | N6-(2-Phenylethyl)adenosine | N6-Phenethyladenosine,N6-Phenylethyladenosine | Adenosine Receptor |
N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1. | |||
T4265 | AZD4635 | HTL1071 | Adenosine Receptor |
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM). | |||
T26641L | Apadenoson TFA | BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA | Adenosine Receptor |
Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS. | |||
T14078 | AB928 | Adenosine Receptor | |
AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1]. | |||
T7021 | ZM241385 | Adenosine Receptor | |
ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor. | |||
T31731 | Evodenoson | DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313 | Adenosine Receptor |
Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumo... | |||
T23336 | SCH442416 | SCH 442416 | Adenosine Receptor |
SCH442416 (SCH 442416) is an selective antagonist of adenosine A2A receptor. SCH442416 binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). | |||
T6552 | Istradefylline | KW-6002 | Adenosine Receptor |
Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails. It has been used in trials studying the treatment and basic science of Drug Ab... | |||
T7183 | CPI-444 | V81444,ciforadenant | Adenosine Receptor |
CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer. | |||
T0437 | Inosine | INO 495,NSC 20262 | ROS , Endogenous Metabolite , Adenosine Receptor |
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties. | |||
T2671 | Regadenoson | CVT-3146,Lexiscan | Adenosine Receptor |
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re... | |||
T40307 | Adenosine receptor antagonist 1 | ||
Adenosine receptor antagonist 1 is a highly selective antagonist for the A2aR adenosine receptor, exhibiting an IC50 value of 0.29 nM. It demonstrates a remarkable 14-fold selectivity towards the A2aR receptor in compari... | |||
T70601 | MDK03855 | ||
MDK03855, also known as A2AR antagonist 19, is an adenosine A2A receptor (A2AR) antagonist. MDK03855 has CAS#1454903-85-5. The last five digit of CAS# was used for name. | |||
T69723 | Taminadenant mesylate | ||
Taminadenant, also known as PBF-509 and NIR-178, is a potent and orally active adenosine A2A receptor antagonist with potential antineoplastic activity. PBF-509 selectively binds to and inhibits A2AR expressed on T lym... | |||
T63151 | IHCH-3064 | ||
IHCH-3064 is a tumour immunotherapeutic agent that targets both the adenosine A2A receptor and HDAC. IHCH-3064 effectively binds A2AR (Ki: 2.2 nM) and selectively inhibits HDAC1 (IC50: 80.2 nM). Prexasertib Mesylate |