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AZD4635

Name: AZD4635
Brand: TargetMol
SKU: T4265
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4265Cas No. 1321514-06-0

Alias HTL1071

AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).

AZD4635

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Purity: 99.90%

Catalog No. T4265Alias HTL1071Cas No. 1321514-06-0

AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).

Pack Size	Price	Availability
1 mg	$31	In Stock
2 mg	$44	In Stock
5 mg	$72	In Stock
10 mg	$118	In Stock
25 mg	$198	In Stock
50 mg	$312	In Stock
100 mg	$480	In Stock
500 mg	$1,060	In Stock
1 mL x 10 mM (in DMSO)	$79	In Stock

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Batch Information

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Purity:99.90%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
Targets&IC50	A2AR:Ki: 1.7 nM
Synonyms	HTL1071

Chemical Properties

Molecular Weight	315.73
Formula	C₁₅H₁₁ClFN₅
Cas No.	1321514-06-0
Smiles	Cc1cc(cc(Cl)n1)-c1nnc(N)nc1-c1ccc(F)cc1
Relative Density.	1.387 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 83.3 mg/mL (263.83 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1673 mL	15.8363 mL	31.6726 mL	158.3632 mL
5 mM	0.6335 mL	3.1673 mL	6.3345 mL	31.6726 mL
10 mM	0.3167 mL	1.5836 mL	3.1673 mL	15.8363 mL
20 mM	0.1584 mL	0.7918 mL	1.5836 mL	7.9182 mL
50 mM	0.0633 mL	0.3167 mL	0.6335 mL	3.1673 mL
100 mM	0.0317 mL	0.1584 mL	0.3167 mL	1.5836 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc