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N6-(2-Phenylethyl)adenosine

Catalog No. T12163   CAS 20125-39-7
Synonyms: N6-Phenethyladenosine, N6-Phenylethyladenosine

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.

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N6-(2-Phenylethyl)adenosine Chemical Structure
N6-(2-Phenylethyl)adenosine, CAS 20125-39-7
Pack Size Availability Price/USD Quantity
5 mg In stock $ 30.00
10 mg In stock $ 47.00
25 mg In stock $ 95.00
50 mg In stock $ 187.00
100 mg In stock $ 327.00
200 mg In stock $ 587.00
500 mg In stock $ 922.00
1 mL * 10 mM (in DMSO) In stock $ 52.00
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Purity: 99.94%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.
Targets&IC50 hA1AR:30.1 nM (ki), hA3AR(ki):0.63 nM (ki), rA1AR:ki:11.8 nM
In vitro The Ki value of human A3 is 0.63 nM. In CHO cells, N6-(2-Phenylethyl)adenosine inhibits A2 with IC50s of 560 nM and 2250 nM for rat and human[1].
Synonyms N6-Phenethyladenosine, N6-Phenylethyladenosine
Molecular Weight 371.39
Formula C18H21N5O4
CAS No. 20125-39-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 0.1 mg/mL (insoluble)

DMSO: 95 mg/mL (255.80 mM), sonification is recommended.

TargetMolReferences and Literature

1. Tchilibon S, et al. Exploring distal regions of the A3 adenosine receptor binding site: sterically constrained N6-(2-phenylethyl)adenosine derivatives as potent ligands. Bioorg Med Chem. 2004 May 1;12(9):2021-34.

Related compound libraries

This product is contained In the following compound libraries:
Neurotransmitter Receptor Compound Library Nucleotide Compound Library Neuronal Signaling Compound Library Bioactive Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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Keywords

N6-(2-Phenylethyl)adenosine 20125-39-7 GPCR/G Protein Neuroscience Adenosine Receptor P1 receptor A1AR derivative N-6-(2-Phenylethyl)adenosine Inhibitor N6-Phenethyladenosine N6 (2 Phenylethyl)adenosine inhibit A3AR N6(2Phenylethyl)adenosine A2AR N6-Phenylethyladenosine adenosine inhibitor

 

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