293t — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1687	Doxycycline	Vibramycin,Doxiciclina,Doxytetracycline,Doxycyclinum	MMP , ribosome , Antibacterial , Antibiotic , Parasite
	Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.		MMP , ribosome , Antibacterial , Antibiotic , Parasite
T1687L	Doxycycline (hyclate)	Doxycycline hydrochloride hemiethanolate hemihydrate,WC2031,Doxycycline hyclate	MMP , ribosome , Antibacterial , Antibiotic
	Doxycycline hyclate (WC2031) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline hyclate has antibacterial activity and antitumor act...		MMP , ribosome , Antibacterial , Antibiotic
T1140	Doxycycline hydrochloride	Doxylin,Vibramycin,Hyclate	MMP , Antibacterial , Antibiotic
	Doxycycline hydrochloride (Hyclate) is a synthetic tetracycline derivative with similar antimicrobial activity.		MMP , Antibacterial , Antibiotic
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
T5318	666-15	CREB inhibitor	Epigenetic Reader Domain
	666-15 (CREB inhibitor) is a potent and selective CREB inhibitor (IC50: 81 nM).		Epigenetic Reader Domain
T10200	9-Hydroxyellipticine hydrochloride		Others
	9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. It exhibits antitumor, antioxidant and catecholamine-releasing activities. 9-Hydroxyellipticine hydrochloride inihibits Hela S-3 and 293T cells (IC50s...		Others
T83857	Soluble Epoxide Hydrolase PROTAC 1a	sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a
	Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its h...
T78758	IHMT-IDH1-053		Isocitrate Dehydrogenase (IDH)
	IHMT-IDH1-053 (compound 16) is an irreversible inhibitor exhibiting high selectivity for the IDH1 R132H mutant, achieving an IC50 of 4.7 nM. It preferentially targets IDH1 mutants over wild-type IDH1 and IDH2, both wild-...		Isocitrate Dehydrogenase (IDH)
T36684	Ipivivint
	Ipivivint, a first-in-class, orally active and potent CDC-like kinase (CLK) inhibitor, inhibits CLK1 (IC50=1.4 μM), CLK2 (IC50=0.002 μM) and CLK3 (IC50=0.022 μM). Ipivivint reduces Wnt pathway signaling gene expression t...