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Search Results for " 11β-hsd1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10160 11β-HSD1-IN-1 Dehydrogenase
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
T72814 11β-HSD1-IN-12 Dehydrogenase
11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and obesity.
T60149 11β-HSD1-IN-11 Dehydrogenase
11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM, respectively. 11β-Hsvd1-in-11 is a compound used as a che...
T67903 11β-HSD1 inibitor 17 Dehydrogenase
11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).
T72022 11β-HSD1 inibitor 19
11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM.
T64321 Octyl-beta-D-glucopyranoside Octyl glucoside,11β-HSD1-IN-11 Others
Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.
T67622 11β-HSD1-IN-7
11β-HSD1-IN-7 is a useful organic compound for research related to life sciences. The catalog number is T67622 and the CAS number is 728-86-9.
T2869 Emodin Frangula emodin SARS-CoV , Casein Kinase , Autophagy
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.
T72911 11β-HSD1-IN-9
11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively. It exhibits competitive interaction with rat 11β-HSD1. This compound holds potent...
T72859 11β-HSD1-IN-10
11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive impairment.
T61593 11β-HSD1-IN-6
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their ...
T65743 11β-HSD1-IN-8
11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.
T2057 BVT 2733 Dehydrogenase
BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.
T14388 AZD 4017 Dehydrogenase
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
T3542 BVT-14225 BVT 14225 Dehydrogenase
BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).
T77606 WAY-311610 Dehydrogenase
WAY-311610 is an 11β-hydroxysteroid dehydrogenase HSD11B1 inhibitor that inhibits the 11β-HSD1 enzyme with an IC = 0.34 μM.It can be used to study neuropathic pain, inflammatory pain, and occipital neuralgia.
T64349 Necroptosis-IN-3 Cyclohexanecarboxamide, N-(2-thienylmethyl)- Necroptosis
Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
T0293 Metyrapone NSC-25265,Su-4885 Others , P450 , Dehydrogenase , Autophagy
Metyrapone (NSC-25265) is an inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
T16510 PF-915275 Dehydrogenase
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF-915275 is an effective and selective human 11β-hydroxyster...
T14383 AZD8329 Dehydrogenase
AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11ß-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM) and dog recombinant 11β-HSD1. AZD8329 has a higher affini...
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