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Transforming Growth Factor-β Receptors, TGF-β Receptors

Transforming growth factor beta (TGFβ) receptors are single pass serine/threonine kinase receptors that belong to TGF-β receptor family. They exist in several different isoforms that can be homo- or heterodimeric. TGF-β is a growth factor and cytokine involved in paracrine signalling and can be found in many different tissue types, including brain, heart, kidney, liver, bone, and testes. Over-expression of TGF-β can induce renal fibrosis, causing kidney disease, as well as diabetes, and ultimately end-stage renal disease.

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Species
Canine (4)
Cynomolgus (6)
Human (32)
Mouse (16)
Rat (4)
Rhesus (3)
Expression System
Baculovirus Insect Cells (5)
HEK293 Cells (60)
Tag
C-6xHis (1)
C-His (16)
C-hFc (28)
C-hFc-6xHis (3)
C-mFc-Avi (4)
GST (2)
His (12)
Tag Free (1)
hFc (10)
Cat No. product name / Synonyms Species Expression System
TMPJ-00304 ALK-1 Protein, Mouse, Recombinant (hFc)
ALK-1 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenet...
TMPJ-00314 ACVR2B Protein, Human, Recombinant (hFc & His)
ACVR2B Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor comple...
TMPJ-00315 ACVR2A Protein, Human, Recombinant (hFc & His)
ACVR2A Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II rec...
TMPJ-00325 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors...
TMPJ-00333 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the acc...
TMPJ-00334 TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the acc...
TMPJ-01158 ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc)
TGFBR1 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Human HEK293 Cells
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TMPK-00328 TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPK-00329 TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
Human HEK293 Cells
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TMPY-00310 ALK-1 Protein, Cynomolgus, Recombinant (His)
ALK-1 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
ALK-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession nu...
TMPY-00444 ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.4 kDa and the accession ...
TMPY-00486 ALK-7 Protein, Human, Recombinant (hFc)
ALK-7 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
ALK-7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.6 kDa and the accession number ...
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
Canine HEK293 Cells
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession...
TMPY-00650 ALK-1 Protein, Human, Recombinant (hFc)
ALK-1 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
ALK-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.4 kDa and the accession number ...
TMPY-00658 ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
Human HEK293 Cells
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39.6 kDa and t...
TMPY-00659 ACVR2A Protein, Human, Recombinant (hFc)
ACVR2A Protein, Human, Recombinant (hFc)
Human HEK293 Cells
ACVR2A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.0 kDa and the accession number...
TMPY-00662 ALK-1 Protein, Mouse, Recombinant (His & hFc)
ALK-1 Protein, Mouse, Recombinant (His & hFc)
Mouse HEK293 Cells
ALK-1 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39 kDa and the acces...
ALK-1 Protein, Mouse, Recombinant (hFc)
TMPJ-00304
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenet...
ACVR2B Protein, Human, Recombinant (hFc & His)
TMPJ-00314
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor comple...
ACVR2A Protein, Human, Recombinant (hFc & His)
TMPJ-00315
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II rec...
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
TMPJ-00325
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors...
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
TMPJ-00333
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the acc...
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TMPJ-00334
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the acc...
ALK-2/ACVR1 Protein, Human, Recombinant (hFc)
TMPJ-01158
Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor fami...
TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms ...
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00306
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpr...
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TMPK-00328
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00329
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from t...
ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
ALK-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession nu...
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc)
TMPY-00444
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.4 kDa and the accession ...
ALK-7 Protein, Human, Recombinant (hFc)
TMPY-00486
ALK-7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.6 kDa and the accession number ...
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession...
ALK-1 Protein, Human, Recombinant (hFc)
TMPY-00650
ALK-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.4 kDa and the accession number ...
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc)
TMPY-00658
ALK-2/ACVR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39.6 kDa and t...
ACVR2A Protein, Human, Recombinant (hFc)
TMPY-00659
ACVR2A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.0 kDa and the accession number...
ALK-1 Protein, Mouse, Recombinant (His & hFc)
TMPY-00662
ALK-1 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 39 kDa and the acces...
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