Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 814.00 | |
500 μg | 5 days | $ 3,250.00 | |
1 mg | 5 days | $ 5,440.00 |
Description | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
Species | Human |
Expression System | HEK293 |
Tag | C-hFc |
Accession Number | P43489 |
Synonyms | IMD16, ACT-135, OX40 homologue, Ly-70, TXGP1L, TNFRSF4, OX40, OX40L receptor, CD134 |
Construction | Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu29-Ala216.[Accession |P43489] |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
Molecular Weight | The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. |
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OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated IMD16 TNFRSF 4 ACT-135 ACT135 OX 40 CD 134 OX40 homologue ACT 135 CD-134 TNFRSF-4 OX-40 Ly-70 TXGP1L TXGP1L TNFRSF4 OX40 IMD 16 IMD-16 OX40L receptor CD134 recombinant recombinant-proteins proteins protein