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Receptor Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. RTKs are part of the larger family of protein tyrosine kinases, encompassing the RTKs proteins which contain a transmembrane domain, as well as the non- RTKs which do not possess transmembrane domains.

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Species
Canine (9)
Cynomolgus (31)
Human (201)
Mouse (77)
Rabbit (1)
Rat (36)
Rhesus (32)
Expression System
Baculovirus Insect Cells (25)
E. coli (3)
HEK293 Cells (348)
Tag
Avi (6)
C-6xHis (7)
C-6xHis-Avi (2)
C-Avi (2)
C-His (149)
C-His-Avi (48)
C-hFc (95)
C-hFc-6xHis (2)
C-hFc-Avi (2)
C-mFc (5)
GST (23)
His (42)
N-His (5)
N-hFc (1)
Tag Free (16)
hFc (13)
Cat No. product name / Synonyms Species Expression System
TMPK-00774 TrkA Protein, Human, Recombinant (aa 33-417, His)
TrkA Protein, Human, Recombinant (aa 33-417, His)
Human HEK293 Cells
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces recepto...
TMPK-00777 CD117 Protein, Mouse, Recombinant (His)
CD117 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
TMPK-00805 CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
TMPK-00847 FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc...
TMPK-00898 EphB3 Protein, Human, Recombinant (His)
EphB3 Protein, Human, Recombinant (His)
Human HEK293 Cells
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC comp...
TMPK-00899 EPHA5 Protein, Human, Recombinant (His)
EPHA5 Protein, Human, Recombinant (His)
Human HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TMPK-00901 TYRO3 Protein, Mouse, Recombinant (His)
TYRO3 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number ...
TMPK-00927 ALK Protein, Mouse, Recombinant (hFc)
ALK Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its gene...
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
TMPK-00979 EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)
EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)
Cynomolgus HEK293 Cells
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. E...
TMPK-00980 EPhA2 Protein, Cynomolgus, Recombinant (hFc)
EPhA2 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. E...
TMPK-00999 EPhA10 Protein, Human, Recombinant (His)
EPhA10 Protein, Human, Recombinant (His)
Human HEK293 Cells
EPhA10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.8 kDa and the accession numb...
TMPK-01019 EPHA5 Protein, Mouse, Recombinant (His)
EPHA5 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric canc...
TMPK-01022 MERTK/Mer Protein, Mouse, Recombinant (His)
MERTK/Mer Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photorecep...
TMPK-01050 PDGF R beta/CD140b Protein, Canine, Recombinant (His)
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
Canine HEK293 Cells
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the ...
TMPK-01084 EPhA10 Protein, Mouse, Recombinant (His)
EPhA10 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
EPhA10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.6 kDa and the accession numb...
TMPK-01270 CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cynomolgus,Rhesus HEK293 Cells
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD11...
TMPK-01280 HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
Cynomolgus,Rhesus HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
TMPK-01322 FGFR4 Protein, Rhesus macaque, Recombinant (His)
FGFR4 Protein, Rhesus macaque, Recombinant (His)
Rhesus HEK293 Cells
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the acces...
TMPK-01327 EPhA10 Protein, Cynomolgus, Recombinant (His)
EPhA10 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
EPhA10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.56 kDa and the accessio...
TrkA Protein, Human, Recombinant (aa 33-417, His)
TMPK-00774
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces recepto...
CD117 Protein, Mouse, Recombinant (His)
TMPK-00777
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00805
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD1...
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the acc...
EphB3 Protein, Human, Recombinant (His)
TMPK-00898
Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC comp...
EPHA5 Protein, Human, Recombinant (His)
TMPK-00899
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TYRO3 Protein, Mouse, Recombinant (His)
TMPK-00901
TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number ...
ALK Protein, Mouse, Recombinant (hFc)
TMPK-00927
Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its gene...
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
TMPK-00943
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. Th...
EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)
TMPK-00979
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. E...
EPhA2 Protein, Cynomolgus, Recombinant (hFc)
TMPK-00980
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. E...
EPhA10 Protein, Human, Recombinant (His)
TMPK-00999
EPhA10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.8 kDa and the accession numb...
EPHA5 Protein, Mouse, Recombinant (His)
TMPK-01019
The aim of the present study was to evaluate ephrin type-A receptor 5 (EphA5) expression and its clinicopathological significance in gastric cancer. Gastric canc...
MERTK/Mer Protein, Mouse, Recombinant (His)
TMPK-01022
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photorecep...
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
TMPK-01050
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the ...
EPhA10 Protein, Mouse, Recombinant (His)
TMPK-01084
EPhA10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.6 kDa and the accession numb...
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TMPK-01270
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells. Among normal BM cells, CD11...
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
TMPK-01280
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
FGFR4 Protein, Rhesus macaque, Recombinant (His)
TMPK-01322
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the acces...
EPhA10 Protein, Cynomolgus, Recombinant (His)
TMPK-01327
EPhA10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 58.56 kDa and the accessio...
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