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Receptor Tyrosine Kinases

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. RTKs are part of the larger family of protein tyrosine kinases, encompassing the RTKs proteins which contain a transmembrane domain, as well as the non- RTKs which do not possess transmembrane domains.

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Species
Canine (9)
Cynomolgus (31)
Human (201)
Mouse (77)
Rabbit (1)
Rat (36)
Rhesus (32)
Expression System
Baculovirus Insect Cells (25)
E. coli (3)
HEK293 Cells (348)
Tag
Avi (6)
C-6xHis (7)
C-6xHis-Avi (2)
C-Avi (2)
C-His (149)
C-His-Avi (48)
C-hFc (95)
C-hFc-6xHis (2)
C-hFc-Avi (2)
C-mFc (5)
GST (23)
His (42)
N-His (5)
N-hFc (1)
Tag Free (16)
hFc (13)
Cat No. product name / Synonyms Species Expression System
TMPK-00429 HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa...
TMPK-00430 HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weig...
TMPK-00448 HER4/ERBB4 Protein, Human, Recombinant (His & Avi)
HER4/ERBB4 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 ...
TMPK-00449 HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated
HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 ...
TMPK-00452 HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
TMPK-00453 HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
TMPK-00457 HGFR/c-Met Protein, Human, Recombinant (His & Avi)
HGFR/c-Met Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
TMPK-00472 AXL Protein, Cynomolgus, Recombinant (His)
AXL Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain dru...
TMPK-00475 FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and th...
TMPK-00481 PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s...
TMPK-00499 HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
TMPK-00529 EPHA5 Protein, Cynomolgus, Recombinant (His)
EPHA5 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TMPK-00533 TYRO3 Protein, Cynomolgus, Recombinant (His)
TYRO3 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession...
TMPK-00563 EPHB2 Protein, Cynomolgus, Recombinant (His)
EPHB2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endoth...
TMPK-00566 ROR2 Protein, Cynomolgus, Recombinant (His)
ROR2 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00572 ROR1 Protein, Canine, Recombinant (His)
ROR1 Protein, Canine, Recombinant (His)
Canine HEK293 Cells
ROR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.2 kDa and the accession numbe...
TMPK-00577 ROR2 Protein, Human, Recombinant (His & Avi)
ROR2 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00578 ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00579 ROR2 Protein, Human, Recombinant (hFc)
ROR2 Protein, Human, Recombinant (hFc)
Human HEK293 Cells
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00686 FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a...
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)
TMPK-00429
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.5 kDa...
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00430
HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weig...
HER4/ERBB4 Protein, Human, Recombinant (His & Avi)
TMPK-00448
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 ...
HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00449
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 ...
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00452
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
TMPK-00453
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, m...
HGFR/c-Met Protein, Human, Recombinant (His & Avi)
TMPK-00457
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
AXL Protein, Cynomolgus, Recombinant (His)
TMPK-00472
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain dru...
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
TMPK-00475
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and th...
PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)
TMPK-00481
Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β s...
HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
TMPK-00499
c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
EPHA5 Protein, Cynomolgus, Recombinant (His)
TMPK-00529
Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 ...
TYRO3 Protein, Cynomolgus, Recombinant (His)
TMPK-00533
TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession...
EPHB2 Protein, Cynomolgus, Recombinant (His)
TMPK-00563
EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endoth...
ROR2 Protein, Cynomolgus, Recombinant (His)
TMPK-00566
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR1 Protein, Canine, Recombinant (His)
TMPK-00572
ROR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.2 kDa and the accession numbe...
ROR2 Protein, Human, Recombinant (His & Avi)
TMPK-00577
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
TMPK-00578
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
ROR2 Protein, Human, Recombinant (hFc)
TMPK-00579
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00686
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the a...
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TargetMol