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Chemokines

Chemokines are a family of small cytokines or signaling proteins secreted by cells that induce directional movement of leukocytes, as well as other cell types, including endothelial and epithelial cells. In addition to playing a major role in the activation of host immune responses, chemokines are important for biological processes, including morphogenesis and wound healing, as well as in the pathogenesis of diseases like cancers. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines have been classified into four main subfamilies: CXC, CC, CX3C and C. All of these proteins exert their biological effects by interacting with G protein-linked transmembrane receptors called chemokine receptors.

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Species
Canine (9)
Cynomolgus (10)
Human (87)
Mouse (45)
Rat (12)
Rhesus (8)
Expression System
Baculovirus-Insect Cells (21)
E. coli (75)
HEK293 (42)
Human Cells (12)
Yeast (18)
Tag
C-6His (10)
C-Fc-6His (2)
C-His (2)
C-His-Avi (3)
C-hFc (4)
His (66)
N-6His (3)
N-His (4)
N-His-Avi (3)
N-His-Sumo (1)
N-hFc (5)
None (13)
NusA (2)
SUMO (3)
Tag Free (37)
hFc (12)
mFc (2)
mucin (1)
Cat No. product name / Synonyms Species Expression System
TMPJ-00005 CCL3 Protein, Human, Recombinant
CCL3 Protein, Human, Recombinant
Human E. coli
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocy...
TMPJ-00006 CXCL1 Protein, Mouse, Recombinant (His)
CXCL1 Protein, Mouse, Recombinant (His)
Mouse Human Cells
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fib...
TMPJ-00008 CXCL10 Protein, Human, Recombinant (hFc & His)
CXCL10 Protein, Human, Recombinant (hFc & His)
Human Human Cells
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in re...
TMPJ-00009 CCL2 Protein, Human, Recombinant
CCL2 Protein, Human, Recombinant
Human E. coli
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine t...
TMPJ-00010 CCL8 Protein, Human, Recombinant
CCL8 Protein, Human, Recombinant
Human E. coli
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
TMPJ-00011 CXCL2 Protein, Mouse, Recombinant
CXCL2 Protein, Mouse, Recombinant
Mouse E. coli
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted ...
TMPJ-00012 CXCL4 Protein, Human, Recombinant (His)
CXCL4 Protein, Human, Recombinant (His)
Human Human Cells
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-bindi...
TMPJ-00018 CCL16 Protein, Human, Recombinant
CCL16 Protein, Human, Recombinant
Human E. coli
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 a...
TMPJ-00019 CCL28 Protein, Human, Recombinant
CCL28 Protein, Human, Recombinant
Human E. coli
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD...
TMPJ-00028 CCL2 Protein, Mouse, Recombinant
CCL2 Protein, Mouse, Recombinant
Mouse E. coli
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence,...
TMPJ-00591 CCL8 Protein, Human, Recombinant (His)
CCL8 Protein, Human, Recombinant (His)
Human Human Cells
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
TMPJ-00673 CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
Mouse Human Cells
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a m...
TMPJ-00760 CXCL7 Protein, Human, Recombinant
CXCL7 Protein, Human, Recombinant
Human E. coli
Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain...
TMPJ-00831 CCL3 Protein, Mouse, Recombinant (His)
CCL3 Protein, Mouse, Recombinant (His)
Mouse E. coli
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be...
TMPJ-00852 CCL2 Protein, Rat, Recombinant (His)
CCL2 Protein, Rat, Recombinant (His)
Rat Human Cells
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and b...
TMPJ-00873 CCL3L1 Protein, Human, Recombinant (His)
CCL3L1 Protein, Human, Recombinant (His)
Human Human Cells
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5...
TMPJ-00884 CXCL9 Protein, Mouse, Recombinant (His)
CXCL9 Protein, Mouse, Recombinant (His)
Mouse Human Cells
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokin...
TMPJ-00952 CXCL12 Protein, Mouse, Recombinant
CXCL12 Protein, Mouse, Recombinant
Mouse E. coli
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs...
TMPJ-00974 XCL1 Protein, Human, Recombinant (hFc & His)
XCL1 Protein, Human, Recombinant (hFc & His)
Human Human Cells
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with hig...
TMPJ-00993 CCL5 Protein, Rat, Recombinant (E. coli, His)
CCL5 Protein, Rat, Recombinant (E. coli, His)
Rat E. coli
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukoc...
CCL3 Protein, Human, Recombinant
TMPJ-00005
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocy...
CXCL1 Protein, Mouse, Recombinant (His)
TMPJ-00006
Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fib...
CXCL10 Protein, Human, Recombinant (hFc & His)
TMPJ-00008
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in re...
CCL2 Protein, Human, Recombinant
TMPJ-00009
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine t...
CCL8 Protein, Human, Recombinant
TMPJ-00010
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
CXCL2 Protein, Mouse, Recombinant
TMPJ-00011
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted ...
CXCL4 Protein, Human, Recombinant (His)
TMPJ-00012
Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-bindi...
CCL16 Protein, Human, Recombinant
TMPJ-00018
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 a...
CCL28 Protein, Human, Recombinant
TMPJ-00019
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD...
CCL2 Protein, Mouse, Recombinant
TMPJ-00028
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence,...
CCL8 Protein, Human, Recombinant (His)
TMPJ-00591
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP...
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
TMPJ-00673
Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a m...
CXCL7 Protein, Human, Recombinant
TMPJ-00760
Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain...
CCL3 Protein, Mouse, Recombinant (His)
TMPJ-00831
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be...
CCL2 Protein, Rat, Recombinant (His)
TMPJ-00852
Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and b...
CCL3L1 Protein, Human, Recombinant (His)
TMPJ-00873
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5...
CXCL9 Protein, Mouse, Recombinant (His)
TMPJ-00884
Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokin...
CXCL12 Protein, Mouse, Recombinant
TMPJ-00952
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs...
XCL1 Protein, Human, Recombinant (hFc & His)
TMPJ-00974
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with hig...
CCL5 Protein, Rat, Recombinant (E. coli, His)
TMPJ-00993
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukoc...
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TargetMol