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Br-PEG7-Br

Catalog No. T17695 CAS 177987-04-1

Br-PEG7-Br is a PEG-based PROTAC Linker that can be used in PROTAC synthesis.

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Br-PEG7-Br, CAS 177987-04-1

Pack Size	Availability	Price/USD	Quantity
25 mg	In stock	$ 40.00
50 mg	In stock	$ 57.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Br-PEG7-Br is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
In vitro	PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Molecular Weight	496.23
Formula	C16H32Br2O7
CAS No.	177987-04-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Related Products

Related compounds with same targets

Pomalidomide-PEG3-C2-NH2 NH2-C6-NH-Boc (+)-Biotin-ONP NH2-C4-NH-Boc Acid-C1-PEG5-Boc BM-PEG3 Boc-NH-PEG4-CH2COOH Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Br-PEG7-Br 177987-04-1 Others PROTAC PROTAC Linker Br PEG7 Br PROTAC Linkers inhibit Br-PEG-7-Br BrPEG7Br Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.