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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T40030 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | halidomide-linker 6 | E3 Ligase Ligand-Linker Conjugate |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate. | |||
T39609 | CIAP1 Ligand-Linker Conjugates 16 | cIAP1 Ligand-Linker Conjugates 16 | |
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs. | |||
T17233 | Vipivotide tetraxetan Linker | PSMA-617 Linker | Others |
Vipivotide tetraxetan Linker (PSMA-617 Linker) is a noncleavable peptide linker utilized in the synthesis of Vipivotide tetraxetan (PSMA-617), a ligand instrumental in producing 177Lu-PSMA-617. This radioactive molecule ... | |||
T39629 | BRD4 ligand-Linker Conjugate 1 | BRD4 ligand-Linker Conjugate 1 | |
BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules uti... | |||
T18639 | Cl-C6-PEG4-O-CH2COOH | PROTAC Linker 4 | Others |
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an effective pegylated PROTAC linker, which is often used in PROTAC synthesis of chloroanes (HaloPROTACs). | |||
T17901 | CIAP1 Ligand-Linker Conjugates 10 | E3 ligase Ligand-Linker Conjugates 47 | Others |
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROT... | |||
T17889 | CIAP1 Ligand-Linker Conjugates 14 | E3 ligase Ligand-Linker Conjugates 36 | Others |
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1]... | |||
T17887 | CIAP1 Ligand-Linker Conjugates 15 | E3 ligase Ligand-Linker Conjugates 34 | Others |
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1... | |||
T17896 | CIAP1 Ligand-Linker Conjugates 4 | E3 ligase Ligand-Linker Conjugates 42 | Others |
cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potenti... | |||
T17885 | CIAP1 Ligand-Linker Conjugates 11 | E3 ligase Ligand-Linker Conjugates 33 | Others |
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in ... | |||
T17900 | CIAP1 Ligand-Linker Conjugates 8 | E3 ligase Ligand-Linker Conjugates 46 | Others |
cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1]. | |||
T34746 | Sulfo-SANPAH Crosslinker | Sulfo-SANPAH Cross-linker,Sulfo-SANPAH Cross linker | Others |
Sulfo-SANPAH Crosslinker (Sulfo-SANPAH Cross linker) is a water-soluble isobisfunctional protein crosslinker. | |||
T17730 | CL2 Linker | Others | |
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2]. | |||
T17893 | CIAP1 Ligand-Linker Conjugates 5 | E3 ligase Ligand-Linker Conjugates 39 | Others |
cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for... | |||
T17894 | CIAP1 Ligand-Linker Conjugates 3 | E3 ligase Ligand-Linker Conjugates 40 | Others |
cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find ... | |||
T17891 | CIAP1 Ligand-Linker Conjugates 2 | E3 ligase Ligand-Linker Conjugates 37 | Others |
cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1]. | |||
T17908 | VHL Ligand-Linker Conjugates 15 | E3 Ligase Ligand-Linker Conjugates 56 | Others |
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1]. | |||
T17895 | CIAP1 Ligand-Linker Conjugates 1 | E3 ligase Ligand-Linker Conjugates 41 | Others |
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1]. | |||
T17892 | CIAP1 Ligand-Linker Conjugates 12 | E3 ligase Ligand-Linker Conjugates 38 | Others |
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creatin... | |||
T17897 | CIAP1 Ligand-Linker Conjugates 13 | E3 ligase Ligand-Linker Conjugates 43 | Others |
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1]. |