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Verubulin hydrochloride

Catalog No. T13298   CAS 917369-31-4
Synonyms: MPC-6827 hydrochloride

Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 breast and other mouse xenograft cancer models.

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Verubulin hydrochloride Chemical Structure
Verubulin hydrochloride, CAS 917369-31-4
Pack Size Availability Price/USD Quantity
1 mg In stock $ 47.00
5 mg In stock $ 128.00
10 mg In stock $ 197.00
25 mg In stock $ 413.00
50 mg In stock $ 618.00
100 mg In stock $ 879.00
500 mg In stock $ 1,790.00
1 mL * 10 mM (in DMSO) In stock $ 143.00
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Purity: 97.93%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 breast and other mouse xenograft cancer models.
Synonyms MPC-6827 hydrochloride
Molecular Weight 315.8
Formula C17H18ClN3O
CAS No. 917369-31-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (71.25 mM)

TargetMolReferences and Literature

1. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71. 2. Sirisoma N, et al. Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration. J Med Chem. 2009 Apr 23;52(8):2341-51.

Related compound libraries

This product is contained In the following compound libraries:
Microtubule-Targeted Compound Library Anti-Cancer Drug Library Anti-Cancer Active Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Compound Library ReFRAME Related Library Bioactive Compound Library NO PAINS Compound Library Cytoskeletal Signaling Pathway Compound Library Clinical Compound Library

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Monomethyl auristatin E Auristatin F VCMMAE Myoseverin TTBK1-IN-2 McMMAF MT189 Batabulin

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Keywords

Verubulin hydrochloride 917369-31-4 Cytoskeletal Signaling Microtubule Associated MPC-6827 Microtubule/Tubulin MPC-6827 Hydrochloride Verubulin MPC6827 Hydrochloride MPC 6827 inhibit MPC6827 Inhibitor MPC-6827 hydrochloride MPC 6827 Hydrochloride Verubulin Hydrochloride inhibitor

 

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