Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 168.00 | |
5 mg | In stock | $ 422.00 | |
10 mg | In stock | $ 677.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,880.00 |
Description | VU 0364739 hydrochloride (VU 0364739 HCl) is a selective and potent inhibitor of phospholipase D2 (PLD2) with IC50s of 20 and 1500 nM for PLD2 and PLD1, respectively.VU 0364739 hydrochloride exhibits potential anticancer activity and induces apoptosis. VU 0364739 hydrochloride has potential anticancer activity, induces apoptosis, and can be used in the study of cancer and metabolic-related diseases. |
Targets&IC50 | PLD2:20 nM, PLD1:1500 nM |
In vitro | MDA-MB-231 cells were cultured in the presence of VU 0364739 hydrochloride (1, 5, and 10 μM) for 24, 48, 72, and 96 hours, followed by determination of cell viability using the WST-1 cell proliferation reagent. The results indicate that VU 0364739 hydrochloride significantly reduces proliferation of MDA-MB-231 cells in a dose- and time-dependent manner[1]. |
Synonyms | VU 0364739 HCl |
Molecular Weight | 482.98 |
Formula | C26H28ClFN4O2 |
CAS No. | 1244640-48-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (20.70 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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VU 0364739 hydrochloride 1244640-48-9 Apoptosis Metabolism Phospholipase VU0364739 Hydrochloride VU-0364739 Hydrochloride VU 0364739 HCl inhibitor inhibit