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Tioxolone

Catalog No. T0515 CAS 4991-65-5

Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.

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Tioxolone, CAS 4991-65-5

Pack Size	Availability	Price/USD
500 mg	In stock	$ 41.00
1 g	In stock	$ 59.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 95.9%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.
Targets&IC50	CAI:91 nM(Ki)

Molecular Weight	168.17
Formula	C7H4O3S
CAS No.	4991-65-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

Ethanol: 32 mg/mL (190.3 mM)

H2O: <1 mg/mL

DMSO: 32 mg/mL (190.3 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Byres M, et al. Acta Crystallogr C, 2004 , 60(Pt 6), o395-o396. 2. Kim BH, et al. Exp Mol Med, 2011, 43(5), 313-321.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max NO PAINS Compound Library Anti-Metabolism Disease Compound Library Target-Focused Phenotypic Screening Library Anti-Cancer Metabolism Compound Library Inhibitor Library Anti-Aging Compound Library Anti-Cardiovascular Disease Compound Library Glycometabolism Compound Library Immunology/Inflammation Compound Library

Related Products

Related compounds with same targets

EMD57033 5-Hexenoic acid, 6-[4-[2-[[(4-chlorophenyl)sulfonyl]amino]ethyl]phenyl]-6-(3-pyridinyl)- Halazone Methyl 2,4-dihydroxybenzoate Zonisamide EMAC10101d Sultiame PIK-93

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tioxolone 4991-65-5 Metabolism Carbonic Anhydrase Carbonate dehydratase Inhibitor inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.