store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway.
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100 mg | In stock | Inquiry |
Description | Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway. |
In vitro |
Taraxerol (0-100 μM; 24 or 48 hours) significantly reduced cell viability to 95% (20 μM), 89.8% (40 μM), 82.6% (60 μM), 72.9% (80 μM), and 63.6% (100 μM). The cell viability of this compound in Hela cells at 20 μM and 100 μM concentrations within 48 hours was 90.7% and 53.6%, respectively.[1] Taraxerol (80 μM; 24 or 48 hours) induces apoptosis and cell death in HeLa cells in a dose-dependent manner. Annexin V/PI double staining method showed that compared with the number of apoptotic cells in the control group at the early (6.5%) and late (0.5%) stages, Taraxerol could significantly induce cell apoptosis (24.2% in the early stage and 16.2% in the late stage).[1] |
In vivo | Taraxerol (5 and 10 mg/kg; i.p.) reduces carrageenan-induced paw edema. The effect of 5mg/kg Taraxerol was significant (p<0.05) only after 4 hours of carrageenan treatment.[2] |
Synonyms | Skimmiol, Alnulin |
Molecular Weight | 426.72 |
Formula | C30H50O |
CAS No. | 127-22-0 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: <0.1 mg/ml
THF: 5 mg/ml (11.72 mM), sonification is recommended.
H2O: <0.1 mg/ml
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Taraxerol 127-22-0 Apoptosis NF-Κb NF-κB Skimmiol Alnulin inhibitor inhibit