Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 46.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects. |
Targets&IC50 | PI3Kδ:3.0 μM (IC50), PI3Kβ:5.4 μM (IC50), PI3Kγ:2.4 μM (IC50) |
In vitro | Quercetin, a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. The pharmacological activities of quercetin that modulate antioxidation/oxidation/kinase-signaling pathways might be differentially elicited in neurons compared with malignant cells, ultimately promoting cell survival or death in a cell type- and metabolism-specific manner. Whereas the broad antioxidation and anti-inflammatory activities of quercetin are important for neuronal survival, the oxidative, kinase- and cell cycle-inhibitory, apoptosis-inducing effects of quercetin are essential for its anticancer effects. [1] |
In vivo | LD50: Mice 159 mg/kg (i.g.) [2] |
Synonyms | Sophoretin |
Molecular Weight | 338.27 |
Formula | C15H10O7·2H2O |
CAS No. | 6151-25-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 15 mg/mL(44.3 mM)
DMSO: 62 mg/mL (183.3 mM)
You can also refer to dose conversion for different animals. More
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Quercetin Dihydrate 6151-25-3 Apoptosis PI3K/Akt/mTOR signaling PI3K Inhibitor Phosphoinositide 3-kinase inhibit Quercetin Sophoretin inhibitor