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Penicillamine

Catalog No. T0983   CAS 52-67-5
Synonyms: d-penicillamin, Dimethyl Cysteine, Artamine, D-(-)-Penicillamine

Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, Artamine chelates with heavy metals and increases their urinary excretion.

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Penicillamine Chemical Structure
Penicillamine, CAS 52-67-5
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Purity: 99.92%
Purity: 99.8%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, Artamine chelates with heavy metals and increases their urinary excretion.
Synonyms d-penicillamin, Dimethyl Cysteine, Artamine, D-(-)-Penicillamine
Molecular Weight 149.21
Formula C5H11NO2S
CAS No. 52-67-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: < 10 mM(< means unknown)

H2O: 50 mg/mL (335.10 mM), sonification is recommended.

TargetMolReferences and Literature

1. Brewer GJ. Expert Opin PharmacOthers. 2006 Feb;7(3):317-24.

TargetMolCitations

1. Kong L, Huang H, Luan S, et al. Inhibition of ASIC1a-Mediated ERS Improves the Activation of HSCs and Copper Transport Under Copper Load. Frontiers in Pharmacology. 2021, 12: 1348.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Active Compound Library Anti-Cancer Approved Drug Library Microbial Natural Product Library Immunology/Inflammation Compound Library Stem Cell Differentiation Compound Library Anti-infective Natural Product Library Clinical Compound Library Bioactive Compounds Library Max

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Keywords

Penicillamine 52-67-5 Microbiology/Virology Antibiotic d-penicillamin Dimethyl Cysteine Inhibitor nitric oxide Drug Metabolite synthase inhibitors D-Penicillamine rheumatoid arthritis pentylenetetrazole seizure mice Artamine cystinuria immune modulator inhibit D-(-)-Penicillamine inhibitor

 

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