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PKA inhibitor fragment (6-22) amide Acetate

Catalog No. T21674L CAS T21674L

Synonyms: PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)

PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).

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PKA inhibitor fragment (6-22) amide Acetate Chemical Structure

PKA inhibitor fragment (6-22) amide Acetate, CAS T21674L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 87.00
2 mg	In stock	$ 125.00
5 mg	In stock	$ 178.00
10 mg	In stock	$ 293.00
25 mg	In stock	$ 491.00
50 mg	In stock	$ 716.00
100 mg	In stock	$ 987.00
1 mL * 10 mM (in DMSO)	In stock	$ 481.00

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Purity: 99.30%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	PKA inhibitor fragment (6-22) amide Acetate is a synthetic peptide which selectively inhibits PKA activity by binding to its substrate site (IC50 < 2 nM).
Targets&IC50	PKA:2.8 nM(ki)

Synonyms	PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base)
Molecular Weight	1928.11
Formula	C82H134N28O26
CAS No.	T21674L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/ml (28.53 mM)

References and Literature

1. Katz BM, et, al. Synthesis, characterization and inhibitory activities of (4-N3[3,5-3H]Phe10)PKI(6-22)amide and its precursors: photoaffinity labeling peptides for the active site of cyclic AMP-dependent protein kinase. Int J Pept Protein Res. 1989 Jun;33(6):439 2. Glass DB, et al. Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase. Protein Sci. 1995 Mar;4(3):405-15.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Tyrosine Kinase Inhibitor Library Bioactive Compound Library NO PAINS Compound Library Bioactive Compounds Library Max Inhibitor Library

Related Products

Related compounds with same targets

A-674563 MLN8054 Rottlerin Bucladesine sodium JAK1/2/3 Inhibitor 1 NH125 Ipatasertib dihydrochloride PKI 14-22 amide, myristoylated Acetate

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PKA inhibitor fragment (6-22) amide Acetate T21674L Tyrosine Kinase/Adaptors PKA PKA inhibitor fragment (6 22) amide Acetate PKA inhibitor fragment amide Acetate PKA inhibitor fragment (622) amide Acetate PKA inhibitor fragment (6-22) amide Acetate(121932-06-7 Free base) inhibitor inhibit

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