Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 42.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 46.00 |
Description | Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes. |
In vivo | Leucobasal is commercially available in the United States as a 2% topical formulation for skin lightening purposes. It acts as a substrate for tyrosinase, thereby functioning as a competitive inhibitor of melanin precursor formation. When diluted in a medium or applied topically on the stratum corneum (RE), Leucobasal leads to reduced pigmentation by decreasing melanin in differentiated keratinocytes and melanocytes. This results in a lowered count of dopa-positive melanocytes induced by Leucobasal. |
Synonyms | 4-Hydroxyanisole, Leucobasal, 4-Methoxyphenol |
Molecular Weight | 124.14 |
Formula | C7H8O2 |
CAS No. | 150-76-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 23 mg/mL (185.3 mM)
Ethanol: 24 mg/mL (193.3 mM)
DMSO: 24 mg/mL (193.3 mM)
You can also refer to dose conversion for different animals. More
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Mequinol 150-76-5 Others 4-Hydroxyanisole Leucobasal inhibit Inhibitor depigmentation Mercurialis 4-Methoxyphenol inhibitor