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Search Results for " cryptochrome "

6

Compounds

Cat No. Product Name Synonyms Targets
T9608 KL201 Others
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1].
T22891 KL001 KL 001,KL-001 Others
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced glu...
T8615 ISOTHIAZOLINE 1,1-DIOXIDE isothiazolidine 1,1-dioxide Others
ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents.
T3005 4-Hydroxychalcone P-Cinnamoylphenol Others , NF-κB
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
T32401 KL044 KL 044,KL-044 Others
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway.
T74743 M47
M47, a small molecule, selectively targets and destabilizes Cryptochrome 1 (CRY1), promoting its degradation within the nucleus. This compound not only initiates apoptosis in Ras-transformed P53-deficient mouse skin fibr...
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