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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9608 | KL201 | Others | |
KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 lengthens the period of circadian rhythms in cells and tissues[1]. | |||
T22891 | KL001 | KL 001,KL-001 | Others |
KL 001 is a Cryptochrome protein (CRY) stabilizer. KL001 prevented ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced glu... | |||
T8615 | ISOTHIAZOLINE 1,1-DIOXIDE | isothiazolidine 1,1-dioxide | Others |
ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents. | |||
T3005 | 4-Hydroxychalcone | P-Cinnamoylphenol | Others , NF-κB |
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice. | |||
T32401 | KL044 | KL 044,KL-044 | Others |
KL044 is a cryptochrome 1 (CRY1) activator that prolongs circadian rhythms and inhibits PER2 activity. KL044 inhibits melanogenesis by inhibiting the cAMP/PKA/CREB pathway. | |||
T74743 | M47 | ||
M47, a small molecule, selectively targets and destabilizes Cryptochrome 1 (CRY1), promoting its degradation within the nucleus. This compound not only initiates apoptosis in Ras-transformed P53-deficient mouse skin fibr... |