Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. Icaritin at low concentration (4 or 8 μMol/L) can promote rat chondrocyte proliferation and inhibit cell apoptosis, while the effect of Icaritin on rat chondrocyte at high concentration was reversed.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 30.00 | |
5 mg | In stock | $ 63.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 197.00 | |
50 mg | In stock | $ 293.00 | |
100 mg | In stock | $ 438.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 68.00 |
Description | Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. Icaritin at low concentration (4 or 8 μMol/L) can promote rat chondrocyte proliferation and inhibit cell apoptosis, while the effect of Icaritin on rat chondrocyte at high concentration was reversed. |
Targets&IC50 | CML-CP:13.4 μM, CML-BC:18 μM, Proliferation (K562 cells):8 μM |
Source |
Synonyms | Anhydroicaritin, Cycloicaritin |
Molecular Weight | 368.38 |
Formula | C21H20O6 |
CAS No. | 118525-40-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (27.15 mM)
H2O: < 1 mM (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Icaritin 118525-40-9 Angiogenesis Apoptosis Autophagy Chromatin/Epigenetic JAK/STAT signaling Stem Cells JAK STAT Anhydroicaritin Cycloicaritin Inhibitor inhibit inhibitor