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Ibotenic acid

Catalog No. TQ0279 CAS 2552-55-8

Synonyms: DL-Ibotenic acid, 鹅膏氨酸, (RS)-Ibotenic acid

Ibotenic acid has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.

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Ibotenic acid, CAS 2552-55-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ibotenic acid has agonist activity at both the NMDA and trans-ACPD or metabotropic quisqualate receptors.
In vitro	Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3 μM as measured by the release of lactate dehydrogenase to the culture media[1].

Synonyms	DL-Ibotenic acid, 鹅膏氨酸, (RS)-Ibotenic acid
Molecular Weight	158.11
Formula	C5H6N2O4
CAS No.	2552-55-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 5 mg/mL (31.62 mM), Need ultrasonic

H2O: 5 mg/mL (31.62 mM), Need ultrasonic and warming

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zinkand WC, et al. Ibotenic acid mediates neurotoxicity and phosphoinositide hydrolysis by independent receptormechanisms. Mol Chem Neuropathol. 1992 Feb-Apr;16(1-2):1-10.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ibotenic acid 2552-55-8 神经科学 NMDAR DL-Ibotenic acid (RS)-Ibotenic acid Ibotenate (+/-)-Ibotenic acid Inhibitor inhibitor inhibit

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