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Hydroxy-α-sanshool

Catalog No. T8307 CAS 83883-10-7

Synonyms: Hydroxy-α-sanshool

Hydroxy- α- sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).

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Hydroxy-α-sanshool, CAS 83883-10-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 98.00
5 mg	In stock	$ 245.00
10 mg	In stock	$ 397.00
25 mg	In stock	$ 663.00
50 mg	In stock	$ 945.00
100 mg	In stock	$ 1,280.00
1 mL * 10 mM (in DMSO)	In stock	$ 268.00

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Purity: 99.47%

Purity: 98.59%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Hydroxy- α- sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).
Targets&IC50	TRPV1:1.1 µM (EC50), TRPA1:69 µM (EC50)
Source	Natural Products > Rutaceae > Zanthoxylum

Synonyms	Hydroxy-α-sanshool
Molecular Weight	263.37
Formula	C16H25NO2
CAS No.	83883-10-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 37.5 mg/mL (142.38 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Koo JY, et al. Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. Br J Pharmacol. 2009 Aug;157(8):1398-409.

Related compound libraries

This product is contained In the following compound libraries：

Neuronal Signaling Compound Library Bioactive Compound Library Natural Product Library for HTS Food as Medicine Compound Library Chinese Pharmacopoeia Natural Product Library Bioactive Compounds Library Max Human Endogenous Metabolite Compound Library Plus Traditional Chinese Medicine Monomer Library Ion Channel Inhibitor Library Human Metabolite Library

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Related compounds with same targets

Lecithin Inosine-5'-triphosphate trisodium salt Spaglumic acid acetate Oleic acid Dihydroxyfumaric acid hydrate Uridine triphosphate 4-Hydroxyphenylpyruvic acid Ecdysone

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Keywords

Hydroxy-α-sanshool 83883-10-7 Membrane transporter/Ion channel Metabolism Endogenous Metabolite TRP/TRPV Channel Hydroxyαsanshool Transient receptor potential channels Inhibitor inhibit TRP Channel Hydroxy α sanshool Hydroxy-α-sanshool inhibitor

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