Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 64.00 | |
5 mg | In stock | $ 128.00 | |
10 mg | In stock | $ 193.00 | |
50 mg | In stock | Inquiry |
Description | Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers. |
In vitro | Garcinone C is active against both of pathogenic (MIC =100 μg/ml) and non-pathogenic leptospira (MIC = 200 μg/ml)[1]. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3, and CDK7. Garcinone C significantly inhibits cell viability of the human nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1, and HONE1 in a time‑ and dose‑dependent manner[2]. |
Source |
Molecular Weight | 414.45 |
Formula | C23H26O7 |
CAS No. | 76996-27-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Garcinone C 76996-27-5 Cell Cycle/Checkpoint DNA Damage/DNA Repair JAK/STAT signaling Microbiology/Virology Neuroscience PI3K/Akt/mTOR signaling Stem Cells Antifection STAT AChR CDK ATM/ATR Cyclin dependent kinase inhibit ATM and RAD3 related Inhibitor Ataxia telangiectasia mutated inhibitor