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Erythrodiol

Catalog No. T8165 CAS 545-48-2

Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.

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Erythrodiol, CAS 545-48-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
In vitro	Erythrodiol (1-15 μM; 24 hours) enhances the ABCA1 protein level in a concentration-dependent manner and reaches significance at 10 and 15 μM.
Cell Research	Cell Line: THP-1 macrophage cells. Concentration: 1 μM, 2.5 μM, 5 μM, 10 μM, and 15 μM. Incubation Time: 24 hours

Molecular Weight	442.7
Formula	C30H50O2
CAS No.	545-48-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 5 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Wang L, et al. Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages. Front Pharmacol. 2017 Jun 13;8:375.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Erythrodiol 545-48-2 Membrane transporter/Ion channel Metabolism ABC Endogenous Metabolite inhibit Inhibitor inhibitor

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