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Diprophylline

Catalog No. T0892    CAS 479-18-5   

Dyphylline is a xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosinereceptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

Pack Size Availability Price/USD Quantity
100 mg In stock 58.00
200 mg In stock 114.00
1 mL * 10 mM (in DMSO) In stock 65.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Dyphylline is a xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosinereceptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

Receptor:

PDE;

Chemical Information:
Molecular Weight 254.25
Formula C10H14N4O4
CAS Number 479-18-5
Solubility

DMSO: 48 mg/mL (188.8 mM)

Water: 47 mg/mL (184.9 mM)

Ethanol: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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