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Cytoskeletal Signaling Akt Delta-Tocotrienol

Delta-Tocotrienol

Catalog No. TMA2474   CAS 25612-59-3

Delta-tocotrienol is a potential angiogenic inhibitor, it (2.5-5 microM) can significantly suppress human colorectal adenocarcinoma cells (DLD-1-CM) -induced tube formation, migration, and adhesion on human umbilical vein endothelial cells.It is also a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offering a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects, it protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling.

Delta-Tocotrienol, CAS 25612-59-3
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1 mg Inquiry 96.00
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Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Delta-tocotrienol is a potential angiogenic inhibitor, it (2.5-5 microM) can significantly suppress human colorectal adenocarcinoma cells (DLD-1-CM) -induced tube formation, migration, and adhesion on human umbilical vein endothelial cells.It is also a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offering a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects, it protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling.
Targets&IC50 Akt,   Bcl-2,   ERK,   p53,   PDK,   PI3K,   VEGFR,  
Molecular Weight 396.61
Formula C27H40O2
CAS No. 25612-59-3

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

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( < 1 mg/ml refers to the product slightly soluble or insoluble )

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