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Dansylcadaverine

Catalog No. T18968   CAS 10121-91-2
Synonyms: Monodansyl cadaverine

Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.

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Dansylcadaverine Chemical Structure
Dansylcadaverine, CAS 10121-91-2
Pack Size Availability Price/USD Quantity
10 mg In stock $ 29.00
50 mg In stock $ 29.00
1 mL * 10 mM (in DMSO) In stock $ 30.00
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Purity: 98.99%
Purity: 98.33%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.
In vitro The amount of actin-thymosin β4 crosslink is very low in the presence of Dansylcadaverine and transglutaminase, while there are large amounts of Dansylcadaverine-labeled thymosin β4 and actin. The amount of cross-link further decreases in the presence of Dansylcadaverine competing for Lys residues of either G-actin or thymosin β4 (100 μM). In the absence of thymosin β4, Dansylcadaverine-labeled actin polymerized to F-actin.
Synonyms Monodansyl cadaverine
Molecular Weight 335.46
Formula C17H25N3O2S
CAS No. 10121-91-2

Storage

keep away from direct sunlight

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (171.7 mM), Sonication is recommended.

TargetMolReferences and Literature

1. Huff T, et al. Thymosin beta(4) serves as a glutaminyl substrate of transglutaminase. Labeling with fluorescentdansylcadaverine does not abolish interaction with G-actin. FEBS Lett. 1999 Dec 24;464(1-2):14-20. 2. Laha D, et al. Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7. Biochim Biophys Acta. 2014 Jan;1840(1):1-9.

Related compound libraries

This product is contained In the following compound libraries:
Autophagy Compound Library Bioactive Compound Library Human Metabolite Library NO PAINS Compound Library Bioactive Compounds Library Max

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Keywords

Dansylcadaverine 10121-91-2 Autophagy Others vacuoles Inhibitor probe autophagic autofluorescent substrate inhibit Monodansyl cadaverine inhibitor

 

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