Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clopimozide (R-29764) acts as a calcium channel antagonist and inhibits [3H] nilandipine binding.Clopimozide is a novel and orally available long-acting antischizophrenic psychostatic compound.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 143.00 | |
5 mg | In stock | $ 360.00 | |
10 mg | In stock | $ 530.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,180.00 | |
100 mg | In stock | $ 1,590.00 | |
500 mg | In stock | $ 3,190.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 439.00 |
Description | Clopimozide (R-29764) acts as a calcium channel antagonist and inhibits [3H] nilandipine binding.Clopimozide is a novel and orally available long-acting antischizophrenic psychostatic compound. |
Targets&IC50 | D2 receptor:0.01 µM, α1-adrenoceptor:0.25 µM, Ca2+ channel:0.017 µM |
In vivo | Clopimozide (5 and 35 mg) in 10 patients' plasma levels were determined with the radio-immunological method. The product exhibited a marked effect on schizophrenic target symptoms (significant at the 0.001 and 0.01 levels), of at least one week's duration, with an absence of sedation and a low degree of extrapyramidal side effects. Clopimozide appears to be particularly suitable for the neuroleptic long-term treatment of compensated schizophrenic patients with insight into their disease.[3] |
Synonyms | R-29764, NSC-335305, NSC 335305, NSC335305, R 29764 |
Molecular Weight | 495.99 |
Formula | C28H28ClF2N3O |
CAS No. | 53179-12-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.96 mg/mL (10 mM)
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Clopimozide 53179-12-7 Membrane transporter/Ion channel Metabolism Calcium Channel R-29764 NSC-335305 NSC 335305 R29764 NSC335305 R 29764 inhibitor inhibit